Murat Flashcards

1
Q

Sulfenilurea is related to which of the following mechanisms?

A) Liver GLUT-2 channels blockade

B) Beta cells Ca + channels activation

C) Homone sensitive lipase activation in adipose cells

D) ATP sensitive K+ channels inhibition in beta cells

E) ATP sensitive K+ channels inhibition in alpha cells

A

D) ATP sensitive K+ channels inhibition in beta cells

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2
Q

Which of the following physiopathological mechanisms related to glomerular filtration is wrong?

A) Diabetic nephropathy - Glomerular membrane surface area increases - GFR increases

B) Heart failure Golmerular hydrostatic pressure decreases-GFR decreases

C) Hypertension-Blood pressure increases-GFR increases.

D) Hyperproteinemia-Colloid Osmotic Pressure increases-GFR decreases

E) Renal calciuria-Capsular hydrostatic pressure increases-GFR increases

A

E) Renal calciuria-Capsular hydrostatic pressure increases-GFR increases

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3
Q

Which is the molecule that establishes the connection between podocytes?

A) Laminine

B) Creatine

C) Nephrin

D) Inulin

E) Calbindin

A

C) Nephrin

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4
Q

Medullar hypertonicity occurs in which part of the kidney and with which transport mediated system?

A) Collector duct- KH antiport system

B) Late distal tubule-Aqouaporin system

C) Early distal tubule- Na-Cl cotransporter system

D) Thick ascending limb of the loop of henle-Na-2C1 K cotransport system

E) Proximal tubule- Ca Mg-K-paracelluler transport system

A

D) Thick ascending limb of the loop of henle-Na-2C1 K cotransport system

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5
Q

Which of the following is the mechanism of action of aldosterone and the kidney cell it affects?

a) In the descending loop of henle cell, it accelerates the Na Hantiport
b) In the ascending loop of henle cell, it slows down the Nat HCO3- antiport
c) In the proximal tubule cell, it slows down the Na amino acid-symport
d) Early distal tubule cell, it accelerates the NaCl- cotransport
e) Late distal tubule cell, it accelerates Na+K+ATPase pomp

A

e) Late distal tubule cell, it accelerates Na+K+ATPase pomp

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6
Q

Which of the following medical conditions is not due to the impairment of Na+ reabsorption mechanisms that occur in early proximal tubular cells?

a) Glucosurial
b) Aminoaciduria

C) Renal hypophosphatemia

d) Renal tubular acidosis
e) Syndrome of Inappropriate Antidiuretic Hormone (SIAH)

A

e) Syndrome of Inappropriate Antidiuretic Hormone (SIAH)

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7
Q

Which of the following is not the anti-aging effect of exercise?

a) Fat mass decreases
b) It causes insulin resistance
c) Bone mineral density increases
d) Muscle strength increases
e) Cholesterol decreases

A

b) It causes insulin resistance

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8
Q

Which one causes kidney failure by increasing the hydrostatic pressure in the Bowman’s capsule?

a) Hemorrhage
b) Anaphylactic shock
c) Myocardial infarction
d) Kidney stones
e) Acute glomerulonephritis

A

e) Acute glomerulonephritis

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9
Q

Which of the following is not a member of the contrinsulinary system?

a) Secretin
b) Cholecystokinin

C) Glucagon

d) Epinephrine
e) VIP

A

e) VIP

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10
Q

Which of the following physiological mechanisms causes stones? decrease in the glomerular filtration rate (GFR) for kidney

a) Decreased of the hydrostatic pressure of Bowman’s space
b) Decreased the filtration coefficient of glomerular capillaries

C) Decreased of the hydrostatic pressure of glomerular capillaries

d) Increased the hydrostatic pressure of glomerular capillaries
e) Increased of the hydrostatic pressure of Bowman’s space

A

e) Increased of the hydrostatic pressure of Bowman’s space

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11
Q

Which of the following insulin synthesis and secretion mechanisms primarily triggers ATP produced from glucose up taken into beta cells?

a) Closes voltage dependent Ca++ channels
b) Increases GLUT 2 synthesis

C) It causes the K+ channels to be closed

d) It activates insulin vesicles inside the cell
e) It directly causes depolarization in beta cell membranes

A

C) It causes the K+ channels to be closed

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12
Q

Which of the following is the localization of a nephron where magnesium and calcium ions are reabsorbed competitively?

a) Late proximal convulated tubule
b) Thick ascending the loop of the Henle

C) Thin decsending the loop of the Henle

d) Early proximal convulated tubule
e) Late distal tubule and collecting duct

A

b) Thick ascending the loop of the Henle

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13
Q

Glomerular filtrasyon bariyerinin doğru sıralaması ?———Endotelial lining-glomerular basemant membrane-podocyte

A

..

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14
Q

Aşağıdakilerden hangisi sadece tubuler bozukluk degildir?–Tubuler Necrosis

A

..

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15
Q

Pankreastaki alfa ve beta hucrelerindee hangisi ortaktir?—-High senstive K channel

A

.

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16
Q

Hangisi karaciğerde insulin mekanizmasıyla ilgili değildir? ——Hormone Sensitive Lipase

A

Hormone Sensitive Lipase

17
Q

Hangisinin GFR yi dusurmesi beklenir?——-Diabetic Nefropathy

A

Diabetic Nefropathy