Multisystems Diseases O/E Findings Flashcards
Name three cutaneous O/E findings seen with Cushing’s syndrome?
Straie
Atrophy
Acne
Name two cutaneous O/E findings seen with primary adrenal failure?
Buccal hyperpigmentation
Palmer crease hyoperpigmentation
Name one cutaneous O/E findings seen with secondary adrenal failure?
Pale skin
Name three cutaneous O/E findings seen with hypothyroidism?
Peri-orbital oedema
Loss of outer 1/3 eyebrow
Dry skin
Name three cutaneous O/E findings seen with hyperthyroidism?
Pre-tibial myxoedema
Exopthalmous
Acropachy
Describe porphyria and what it is associated with?
Blood filled blister in the back of the hands
Associated with haemachromatosis
Female pts = hirtuism
Which lipid disorder is associated with tendon xanthalasma?
Familial hypercholestrolaemia
Which lipid disorder is associated with erruptive xanthoma and what other O/E may be seen?
Hypertriglyceridaemia
Also with lipaemia retinalis
Which lipid disorder is associated with straie-palmer xanthalasma?
Reminant hyperlipaemia (APoE2)
Which conditions are associated with acanthosis nigrans?
DM
Stomach cancer
Which O/E finding typically on the legs may be seen in a patient with newly presenting/poorly controlled DM?
Necrobiosis lipodicum - skin biopsy diagnostic (purple patches on the shins)
Name three conditions associated with pyoderma gangrenosum?
IBD
Lekaemia
Myeloma
What is Sweet’s syndrome?
Sweet’s syndrome (SS), or acute febrile neutrophilic dermatosis is a skin disease characterized by the sudden onset of fever, an elevated white blood cell count, and tender, red, well-demarcated papules and plaques that show dense infiltrates by neutrophil granulocytes on histologic examination
What cutaneous O/E finding may be seen in patients with cutanouse T-cell lymphoma?
Mycosis Fungoids - looks like psoriasis - turns into tumours
Name the two O/E findings along with three symptoms of a patient presenting with measles and describe the incubation period?
Mobilliform rash
Koplik spots in mouth
Coryza, cough, conjunctivitis (3C)
10 day incubation period
Describe the three stage course of syphalis?
- Painless chnacre on dick
- Copper papules on soles and palms and snail-track ulcers
- Gummata
Name five causes of errythema nodosum?
- Strep infection
- IBD
- Sarcodosis
- Hep B vaccination
- Cat scratch disease
Describe the three features of Reiter’s syndrome and name two O/E findings?
- Conjunctivitis
- Arthritis
- Urethritis
Kerratoderma blenorrhagia
Cicinate balanitis
Describe three features associated with Behcets and name two O/E findings?
- Oral ulcers
- Genital ulcers
- Uveitis
Pyoderma gangrenosum
Pathergy (cut open and they ulcerate)
Name two O/E findings seen with vascular changes within CT diseases?
Livido reticularis
Nail fold changes
Describe three O/E findings seen with scurvy?
Corkscrew hairs
Bleeding gums
Perifollicular haemorrhages
Describe the three features of pellagra (vit B nicin deficiency)?
Dermatitits
Diarrhoea
Dementia
Describe three features seen with pseudoxathoma elasticum?
Angoid streaks on fundoscopy
Elastomas (look like a plucked chicken)
Arterial aneurysms
Name four O/E features seen with neurofibromatosis?
- Axillary freckling
- Cafe au lait spots
- Neurofibromas
- Lisch nodules (within the eyes)