multisystem triads and complexes

Question 1

Carney complex

Answer 1

• atrial myxoma (often bilat)
• large cell calcifying Sertoli cell testicular tumor
• primary pigmented nodular adrenocortical disease (PPNAD) –> Cushing’s
• thyroid follicular adenoma
• psammomatous melanocytic schwannoma
• growth-hormone prodcuing adenoma (–> acromegaly)
• skin hyperpigmentation

Question 2

Carney Triad

Answer 2

Carney triad is a rare syndrome defined by the coexistence of three tumors:

extra-adrenal paraganglioma;
gastric gastrointestinal stromal tumors (GIST);
pulmonary chondroma In most cases, only 2 of the 3 tumors are present at the time of diagnosis. It typically affects young people.

Question 3

extra-adrenal paraganglioma;
gastric gastrointestinal stromal tumors (GIST);
pulmonary chondroma In most cases, only 2 of the 3 tumors are present at the time of diagnosis. It typically affects young people.

Answer 3

Carney triad

Question 4

• atrial myxoma (often bilat)
• large cell calcifying Sertoli cell testicular tumor
• primary pigmented nodular adrenocortical disease (PPNAD) –> Cushing’s
• thyroid follicular adenoma
• psammomatous melanocytic schwannoma
• growth-hormone prodcuing adenoma (–> acromegaly)
• skin hyperpigmentation

Answer 4

Carney complex