Multiple Sclerosis Flashcards
1
Q
what is multiple sclerosis?
A
chronic autoimmune disease demyelinating the CNS
2
Q
what are the different types of MS?
A
relapsing, progressive, or both
3
Q
what is classed as active MS?
A
2 relapses in the past 2 years despite treatment with interferon beta
4
Q
what is done to manage symptoms?
A
-spasticity: baclofen, diazepam, tizanidine and dantrolene
-Relapse: methylprednisolone
-Oscillopsia (objects appear to vibrate): gabapentin
-Mood alteration: amitriptyline
-Fatigue: amantadine or fampridine
5
Q
how should baclofen be initated?
A
-increase doses slowly, to avoid major side effects such as sedation and hyptonia