Multiple Sclerosis Flashcards
1
Q
What is MS?
A
Autoimmune disease where immune system attacks and destroys myelin sheaths around neurons and weakens signal transduction
Inflammation of neurons
2
Q
Diagnosis of MS?
A
MRI
3
Q
Drugs used for MS?
A
Glatiramer
Natalizumab
Interferon B
Corticosteroids (dexamethasone, prednisone)
Chemotherapeutic agents (cyclophosphamide, azathioprine)
Mitoxantrone
Fingolimod
Dalfampridine
4
Q
Moa of dalfampridine?
A
K channel blocker, improves walking speed
5
Q
Moa of glatiramer
A
Myelin protection by decoying t cell attacks
6
Q
Moa of natalizumab
A
Attaches to cells that attack myeline sheaths
