Multiple Pregnancy Flashcards

1
Q

Multiple pregnancy

A

Refers to a pregnancy with more than one fetus.

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2
Q

Monozygotic

A

Identical twins (from a single zygote)

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3
Q

Dizygotic

A

Non-identical (from two different zygotes)

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4
Q

Monochorionic

A

Share a single placenta

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5
Q

Dichorionic

A

Two separate placentas

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6
Q

What conditions give the best outcome

A

Diamniotic, dichorionic twin pregnancies

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7
Q

How is a multiple pregnancy diagnosed

A

Diagnosed on the booking ultrasound scan.

USS can be used to determine the:

  • Gestational age
  • Number of placentas (chorionicity) and amniotic sacs (amnionicity)
  • Risk of Down’s syndrome (as part of the combined test)
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8
Q

How do dichorionic diamniotic twins present on USS

A

Have a membrane between the twins, with a lambda sign or twin peak sign

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9
Q

How do monochorionic diamniotic twins present on USS

A

Have a membrane between the twins, with a T sign

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10
Q

How do Monochorionic monoamniotic twins present on USS

A

Have no membrane separating the twins

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11
Q

Risks of a multiple pregnancy to the mother

A
Anaemia
Polyhydramnios
Hypertension
Malpresentation
Spontaneous preterm birth
Instrumental delivery or caesarean
Postpartum haemorrhage
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12
Q

Risks of a multiple pregnancy on the fetus

A
Miscarriage
Stillbirth
Fetal growth restriction
Prematurity
Twin-twin transfusion syndrome
Twin anaemia polycythaemia sequence
Congenital abnormalities
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13
Q

Twin-Twin Transfusion Syndrome pathophysiology

A

When the foetuses share a placenta, one fetus (the recipient) may receive the majority of blood from the placenta while the other fetus (the donor) is starved

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14
Q

What happens to the recipient in twin to twin transfusion

A

The recipient can become fluid overload

  • Heart failure
  • polyhydramnios
  • large size
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15
Q

What happens to the donor in twin to twin transfusion

A

Growth restriction
Oligohydramnios
Anaemia
Small size

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16
Q

Management of twin to twin transfusion

A

Referred to specialist fetal medicine centre

Severe - laser treatment to destroy the connection between the 2 blood supplies

17
Q

Twin Anaemia Polycythaemia Sequence

A

One twin becomes anaemic whilst the other develops polycythaemia (raised haemoglobin)

More gradual

18
Q

Monitoring for multiple pregnancies

A

Additional ultrasound scans:

  • 2 weekly scans from 16 weeks for monochorionic twins
  • 4 weekly scans from 20 weeks for dichorionic twins
19
Q

Planned birth for multiple pregnancy

A

Planned birth is offered between:

32 - 33 + 6 weeks for uncomplicated monochorionic monoamniotic twins

36 - 36 + 6 weeks for uncomplicated monochorionic diamniotic twins

37 and 37 + 6 weeks for uncomplicated dichorionic diamniotic twins

Before 35 + 6 weeks for triplets

20
Q

What is given before the birth in a multiple pregnancy

A

Corticosteroids

21
Q

Monoamniotic twins delivery

A

Require elective caesarean section at between 32 and 33 + 6 weeks

22
Q

Diamniotic twins delivery

A

Vaginal delivery - possible when the first baby has a cephalic presentation

Caesarean section - may be required for the second baby

Elective caesarean - advised when the presenting twin is not cephalic presentation