Multiple Endocrine neoplasia Flashcards
1
Q
What are multiple endocrine syndromes?
A
Syndrome where functioning hormone-producing tumours in multiple organs
2
Q
How are Multiple endocrine syndromes inherited?
A
Autosomal dominant inheritence
3
Q
What are the main features of MEN-1 syndrome?
A
3 P’s + A
- Parathyroid hyperplasia
- Pituitary - Prolactinoma/GH secreting tumours
- Pancreatic endocrine tumours
- Adrenal tumours
4
Q
What are features of MEN-2a?
A
TAP
- Medullary Thyroid cancer
- Adrenal Phaeochromocytoma
- Parathyroid hyperplasia
5
Q
What are features of MEN-2b?
A
MTC + Adrenal phaeo + Mucosal neuroma + Marfanoid appearance
