Multiple Choice Questions- bio Flashcards
In the formation of the secondary structure of a protein, which of the following are most responsible for holding an alpha-helix region in its helical form?
A. Ionic bonds
B. Hydrogen bonds
C. Hydrophobic interactions
D. Van der waals interactions
B. Hydrogen bonds
Which of the following is an anticodon?
A. The part of a DNA molecule that codes for chain termination
B. A 3-nucleotide sequence of an mRNA molecule
C. A specific part of a tRNA molecule
D. A nucleotide triplet of an rRNA molecule
C. A specific part of a tRNA molecule
Which of the following is not a polymer?
A. Glucose
B. Starch
C. Cellulose
D. DNA
A. Glucose
Which bonds are created during the formation of the primary structure of a protein?
A. Peptide bonds
B. Hydrogen bonds
C. Disulphide bonds
D. Phosphodiester bonds
A. Peptide bonds
What maintains the secondary structure of a protein?
A. Peptide bonds
B. Hydrogen bonds
C. Disulphide bonds
D. Phosphodiester bonds
B. Hydrogen bonds
If a DNA sample were composed of 10% thymine, what would be the percentage of guanine?
A. 10
B. 20
C. 40
D. 80
C. 40
Which of the following statements best summarises the structural differences between DNA and RNA?
A. RNA is a protein, whereas DNA is a nucleic acid
B. DNA is a protein, whereas RNA is a nucleic acid
C. DNA nucleotides contain different sugar than RNA nucleotides
D. RNA is double helix but DNA is single stranded
C. DNA nucleotides contain a different sugar than RNA nucleotides
What is the structural feature that allows DNA to replicate?
A. Sugar phosphate backbone
B. Complementary pairing of the nitrogenous bases
C. Disulphide bonding( bridging) of the two helixes
D. Twisting of the molecule to form an a helix
B. Complementary pairing of the nitrogenous bases
Enzymes are ..
A. Carbohydrates
B. Lipids
C. Proteins
D. Nucleic acids
C. Proteins
Polypeptides are assembled from
A. Hexoses
B. Glycerol
C. Nucleotides
D. Amino acids
D. Amino acids
What is the name given to the processes in which the information encoded in a strand of mRNA is used to construct a protein?
A. RNA processing
B. Gene expression
C. Transcription
D. Translation
D. Translation
What is the name given to the processes in which a strand of DNA is used as a template for the manufacture of a strand of pre-mRNA?
A. RNA processing
B. Polypeptide formation
C. Transcription
D. Translation
C. Transcription
Which of the following is a false statement regarding deoxyribonucleic acid( DNA)?
A. Each deoxyribonucleic acid molecule is composed of two long chains of nucleotides arranged in a double helix
B. Genes are composed of deoxyribonucleic acid
C. DNA is composed of chemical building blocks called nucleotides
D. DNA is an enzyme that puts together amino acids to make a protein
D. DNA is an enzyme that puts together amino acids to make a protein
A type of protein critical to all cells is an organic catalyst called
A. Vitamin
B. Enzyme
C. Metabolite
D. Nutrient
B. Enzyme
What is the chemical mechanism by which cells make polymers from monomers?
A. Hydrolysis
B. Dehydration reactions
C. Ionic bonding of monomers
D. The formation of disulphide bridges between monomers
B. Dehydration reactions
There are 20 different amino acids. What makes one amino acid different from another?
A. Different carboxyl groups attached to an alpha carbon
B. Different amino groups attached to an alpha carbon
C. Different side chains( R groups) attached to an alpha carbon
D. Different alpha carbons
C. Different side chains (R groups) attached to an alpha carbons
Polysaccharides, lipids and proteins are similar in that they
A. Are synthesised from monomers by the process of hydrolysis
B. Are synthesised from monomers by dehydration reactions
C. Are synthesised as a result of a peptide bond formation between monomers
D. Are decomposed into their subunits by dehydration reactions
B. Are synthesised from monomers by dehydration reactions
Which type of interaction stabilises the alpha helix and the beta sheet?
A. Nonpolar covalent binds
B. Ionic bonds
C. Hydrogen bonds
D. Peptide bonds
C. Hydrogen bonds
The alpha helix and beta sheet are both common polypeptide forms found in which level of the protein structure?
A. Primary
B. Secondary
C. Tertiary
D. Quaternary
B. Secondary
The tertiary structure of a protein is the
A. Bonding together of several polypeptide chains by weak bonds
B. Order in which amino acids are joined in a polypeptide chain
C. Unique three-dimensional shape of the fully folded polypeptide chain
D. Organisation of a polypeptide chain into an alpha helix or beta pleated sheet
C. Unique three dimensional shape of the fully folded polypeptide chain into an alpha helix or beta pleated sheet
Which of the following best describes the flow of information in eukaryotic cells?
A. DNA->RNA->proteins
B. RNA->proteins-> RNA
C. Proteins->DNA->RNA
D. RNA-> DNA-> proteins
A. DNA -> RNA-> proteins
The differences between the sugar in DNA and the sugar in RNA is that the sugar in DNA
A. Is a six carbon sugar and the sugar in RNA is a five carbon sugar
B. Can form a double stranded molecule
C. Has a six membered ring of carbon and nitrogen atoms
D. Has one less oxygen atom
D. Has one less oxygen atom
Which of the following store and transmit hereditary information?
A. Carbohydrates
B. Lipids
C. Proteins
D. Nucleic acid
D. Nucleic acids
Why does the DNA double helix have a uniform diameter?
A. Purines pair with pyrimidines
B. C nucleotides pair with A nucleotides
C. Deoxyribose sugars bind with ribose sugars
D. Nucleotides bind with nucleosides
A. Purines pair with pyrimidines
In an analysis of the nucleotide composition of DNA which of the following will be found?
A. A=C
B. A=G and C=T
C. A+C = G+T
D. G+C= T+A
C. A+C = G+T
What is the chemical mechanism by which cells make polymers from monomers?
A. Hydrolysis
B. Dehydration reactions
C. Ionic bonding of monomers
D. The formation of disulphide bridges between monomers
B. Dehydration reactions
Which of the following synthesises short segments of RNA?
A. Helicase
B. DNA polymerase II
C. Ligase
D. Primase
D. Primase
The genetic code is essentially the same for all organisms. From this one can logically assume all of the following except
A. A gene from an organism could theoretically be expressed by any other organism
B. All organisms have a common ancestor
C. DNA was the first genetic material
D. The same codons in different organisms usually translate into the same amino acids
C. DNA was the first genetic material
What is a ribozyme?
A. An enzyme that uses RNA as a substrate
B. An RNA with enzyme activity
C. An enzyme that synthesises RNA as part of the transcription process
D. An enzyme that synthesises RNA primers during DNA replication
B. An RNA with enzymic activity
What are the coding segments of a stretch of eukaryotic DNA called?
A. Introns
B. Exons
C. Codons
D. Replicons
B. Exons
What is the most abundant type of RNA?
A. mRNA
B. tRNA
C. rRNA
D. hnRNA
C. rRNA
Which of the following is not true of a codon?
A. It consists of three nucleotides
B. It may code for the same amino acid as another codon
C. It never codes for more than one amino acid
D. It extends from one end of a tRNA molecule
D. It extends form one of a tRNA molecule
The primary structure of a protein molecule is determined by Sequence of:
A. Single nucleotides in mRNA
B. Nucleotide triplets in tRNA
C. Nucleotide triplets in mRNA
D. Nucleotide in rRNA
C. Nucleotide triplets in mRNA
Which of the following statement on the bio synthesis of Nucleic acids and proteins is false?
A. Incorporation of each amino acid into a newly synthesised Polypeptide is defined by a nucleotide triplet in mRNA.
B. The set of rules which match appropriate amino acids to individual codons is known as the genetic code.
C. the end of a translation process is signalled by a termination codon
D. A sequence of amino acids in a polypeptide chain is termed a structural gene
D. A sequence of amino acids in a polypeptide chain is termed a structural gene
RNA synthesis takes place in
A. Lysosomes and peroxisomes
B. Mitochondria and chloroplasts
C. Ribosomes and centrioles
D. Rough endoplasmic reticulum
B. Mitochondria and chloroplasts
The most abundant protein in the body is
A. DNA
B. starch
C. Cellulose
D. Collagen
D. Collagen
Which of these statement about the polypeptides in cells is wrong?
A. They are a polymer of y-amino acids linked by peptide bonds
B. The sequence of amino acids is determined by instructions in the cell’s DNA
C. They have an amino group at one end of the polymer
D. They are called proteins if they fold into a specific shape
A. They are a polymer of y-amino acids linked by peptide bonds
An infectious agent that appears to have no Nucleic acid is a
A. Bacterium
B. Bacteriophage
C. Virus
D. Prion
D. Prion
What are prions
A. Misfold versions of normal brain protein
B. Tiny molecules of RNA that infect plants
C. Viruses that invade bacteria
D. A mobile segment of DNA
A. Misfolded versions of normal Brain protein
The ability to reproduce themselves is a property that viruses share with living systems. Viruses can therefore replicate
A. In vitro in the presence of nucleotides and amino acids
B. In vitro in the process of nucleotides, amino acids and ATP
C. Both in a living and a dead cell
D. Only in a metabolically active cell
D. Only in a metabolically active cell
Which of the statement concerning viruses is true
A. Viruses include only one of Nucleic acid, either DNA or RNA
B. Viruses usually contain all known types of Nucleic acids (DNA, mRNA, rRNA, tRNA)
C. viral particles are capable of ATP synthesis
D. Synthesis of viral proteins takes place on specific viral ribosomes
A. Viruses include only one kind of nucleic acid either DNA or RNA
A bacteriophage is
A. Term for a special macrophage
B. A white blood cell capable of phagocytosis of bacteria
C. Virus that lyses bacteria
D, bacterium capable of phagocytosis
C. Virus that lyses bacteria
All of the following are part of a prokaryotic cell except
A. DNA
B. A plasma membrane
C. Ribosomes
D. Endoplasmic reticulum
D. Endoplasmic reticulum
Which of the following statements concerning prokaryotic and eukaryotic cells is not correct?
A. Prokaryotic cells lack a membrane bound nucleus
B. Prokaryotic cells contain small membrane enclosed organelles
C. Eukaryotic cells contain a membrane bound nucleus
D. DNA or deoxyribonucleic acids is present is both prokaryotic and eukaryotic cells
B. Prokaryotic cells contain small membrane bound organelles
Which statement about the genomes of prokaryotes is correct?
A. Prokaryotic genomes are diploid throughout most of the cell cycle
B. Prokaryotic chromosomes are sometimes called plasmids
C. Prokaryotic cells have multiple chromosomes “packed” with a relatively large amount of protein
D. The prokaryotic chromosomes is not contained within a nucleus but rather is found at the nucleoid region
D. The prokaryotic chromosomes is not contained within a nucleus but rather is found in the nucleoid region
Organelles that do not contain dna include
A. Ribosomes
B. Mitochondria
C. Chloroplasts
D. Nuclei
A. Ribosomes
Which structure is common to both plant and animal cells?
A. Chloroplast
B. Wall made of cellulose
C. Mitochondria
D. Centriole
C. Mitochondria
Homologous chromosomes
A. Are identical in shape and have different loci
B. Differ in shape and size and have identical loci
C. Pair during meiosis
D. Pair during mitosis
C. Pair during meiosis
Which of the following is true?
A. Human cells contain one pair of sex chromosomes and 23 pairs of autosomes
B. Chromosome banding is a procedure for identification of structural abnormalities in single chromosomes
C. Haemophilia is an autosomal dominant trait
D. Chromosomal constitution of the sperm is XY
B. Chromosome banding is procedure fo the identification for the structural abnormalities in single chromosomes
Which organelle do not have membrane structure?
A. Mitochondria
B. Endoplasmic reticulum
C. Golgi complex
D. Ribosomes
D. Ribosomes
Multinucleated cells are
A. Lymphocytes
B. Grandular epithelial cells
C. Neurones
D. Muscle fibres of skeletal muscles
D. Muscle fibres of skeletal muscles
What is a chromatid?
A. A replicate chromosome
B. A chromosome found outside the nucleus
C. A special region that holds two centromeres together
D. Another name for the chromosomes found in genetics
A. A replicate chromosome
Which term describes centromeres uncoupling, sister chromatids separating and the two new chromosomes moving to opposite poles of the cell?
A. Telophase
B. Anaphase
C. Metaphase
D. Prophase
B. Anaphase
If cells in the process of dividing are subjected to colchicine, a drug that interferes with the functioning of the spindle apparatus, at which stage will mitosis be arrested?
A. Anaphase
B. Prophase
C. Telophase
D. Metaphase
D. Metaphse
At which stage of mitosis are the chromosomes usually photographed in the preparation of a karyotype?
A. Prophase
B. Metaphase
C. Anaphase
D. Telophase
B. Metaphase
In which of the cell cycle does nuclear dna replicate?
A. G1
B. G2
C. M
D. S
D. S
Where does glycolysis take place
A. Mitochondrial matrix
B. Mitochondrial outer membrane
C. Mitochondrial inner membrane
D. Cytosol
D. Cytosol
In addition to ATP, what are the end products of glycolysis?
A. CO2 and H2O
B. CO2 and pyruvate
C. NADH and pyruvate
D. H2O, FADH2 and citrate
C. NADH and pyruvate
Where are the proteins of the electron transport chain located?
A, mitochondrial outer membrane
B. Mitochondrial inner membrane
C, mitochondrial intermembrane space
D. Mitochondrial matrix
B. Mitochondrial inner membrane
Energy released by the electron transport chain is used to pump H+ ions into which location?
A.Cytosol
B. Mitochondrial inner membrane
C. Mitochondrial intermembrane space
D. Mitochondrial matrix
C. Mitochondrial intermembrane space
The direct energy source that drives ATP synthesis during respiratory oxidative phosphorylation is
A. Oxidation of glucose to co2 and water
B. The thermodynamic ally favourable flow of electrons from NADH to the mitochondrial electron transport carriers
C. The final transfer of electrons to oxygen
D. The difference in H+ concentrations on opposite sides of the inner mitochondrial membrane
D. The difference in H+ concentrations on opposite sides of the inner mitochondrial membrane
WHere is atp synthase located in the mitochondrion
A. Electron transport chain
B outer membrane
C. Inner membrane
D. Mitochondrial matrix
C. Inner membrane
Which of the following occurs in the cytosol of a eukaryotic cell
A. Glycolysis and fermentation
B. Oxidation of pyruvate to acetyl CoA
C. Citric acid cycle
D. Oxidative phosphorylation
A. Glycolysis and fermentation
The direct energy source that drives atp synthesis during respiratory oxidative phosphorylation is
A. Oxidation of glucose to co2 and water
B. The thermodynamic ally favourable flow of electrons from NADH to the mitochondrial electron transport carriers
C. The final transfer of electrons to oxygen
D. The difference in H+ concentrations on opposite sides of the inner mitochondrial membrane
D. The difference in H+ concentration on opposite sides of the inner mitochondrial membrane
Where is atp synthase located in the mitochondria
A. Electron transport chain
B. Outer membrane
C. Inner membrane
D. Mitochondrial matrix
C. Inner membrane
Which of the following occurs in the cytosol of a eukaryotic cell
A. Glycolysis and fermentation
B. Oxidation of pyruvate to acetyl coA
C. Citric acid cycle
D. Oxidative phosphorylation
A. Glycolysis and fermentation
Which metabolic pathway is common to both cellular respiration and fermentation
A. Oxidation of pyruvate to acetyl coA
B.citric acid cycle
C. Oxidative phosphorylation
D. Glycolysis
D. Glycolysis
How many different types of gamates could be produced by an individual with the arbitrary genotype of AAbbCCDdEe
A. Two
B. Four
C. Eight
D. More than eight
B. Four
If two parents are heterozygous (Aa) at a single locus give rise to offspring that are 25 percent AA, 50 percent Aa, and 25 percent aa, then all the following are true except
A. The parents are diploid organisms
B. The a allele is recessive lethal
C. The alleles assort independently
D. The probability that a given gamete will receive A is one half
B. The a allele is recessive lethal
Recessive lethal gene can code for either dominant or recessive traits but they do not actually cause death unless an organism carries two copies of the lethal allele
How many unique gametes could be produced through independent assortment by an individual with the genotype AaBbCCdEE
A. Four
B. Eight
C. 16
D. 32
B. Eight
A sexually reproducing animal has two unlinked genes, one for head shape (H) and one for tail length(T). It’s genotype is HhTt. Which of the following genotype is possible in a gamete from this organism
A. HT
B. Hh
C. HhTt
D. tt
A. HT
Mendel’s observation of the segregation of alleles in a gamete formation has its basis in which of the following phases of cell division
A. Prophase I of meiosis
B. Prophase II of meiosis
C. Metaphase I of meiosis
D. Anaphase I of meiosis
D. Anaphase I of meiosis
In certain plants tall is dominant to short. If a heterozygous plant is crossed with a homozygous tall plant what is the probability that the offspring will be short
A. 1/2
B. 1/4
C. 1/6
D. 0
D. 0
In a cross AaBbCc x AaBbCc what is the probability of producing the genotype AABBCC?
A. 1/8
B. 1/16
C. 1/32
D. 1/64
D. 1/64
Of the following which is the most current description of a gene
A. A unit of heredity that causes formation of a phenotypic characteristic
B. A dna subunit that codes for a single complete protein
C. A dna sequence that is expressed to form a functional product: either rna or polypeptide
D. A discrete unit of hereditary information that consists of a sequence of amino acids
C. A dna sequence that is expressed to form a functional product either rna or polypeptide
The number of different phenotypes in F2 generation of dihybrids with complete dominance (AaBb x AaBb) is
A. 1
B. 2
C. 3
D. 4
D. 4
One of mendel’s key discoveries was that
A. Organisms had two hereditary factor for all trait
B. Blending was a common occurrence in sexually reproducing organisms
C. Gametes contained two heredity factor for each trait
D. Ova were larger than sperms
A. Organisms had two hereditary factors for all traits
All offspring of a white hen and a black rooster are grey. The simplest explanation of this pattern of inheritance is
A. Pleiotropy
B. Sex linkage
C. Incomplete dominance
D. Independent assortment
C. Incomplete dominance
A cross between homozygous purple flowered and homozygous white flowered pea plants results in offspring with purple flowers. This demonstrates
A. The blending model of genetics
B. True breeding
C. Dominance
D. A dihybrid cross
C. Dominance
Given the parents AABBCc x AabbCc assume simple dominance and independent assortment. What proportion of the progeny will be expected to phenotypically resemble the first parent
A. 1/4
B. 1/8
C. 3/4
D. 3/8
C. 3/4
A 1:2:1 phenotypic ratio in the F2 generation of a mono hybrid cross is a sign of
A. Complete dominance
B. Multiple alleles
C. Incomplete dominance
D. Polygenic inheritance
C. Incomplete dominance
Skin colour in a certain species of fish is inherited via a single gene with four different alleles. How many different types of gametes would be possible in this system?
A. 2
B. 4
C. 8
D. 16
B. 4
Which describes the ABO blood group system?
A. Incomplete dominance
B. Multiple alleles
C. Pleiotropy
D. Epistasis
B. Multiple alleles
Which describes the ABO blood group system?
A. Incomplete dominance
B. Multiple alleles
C. Pleiotropy
D. Epistasis
B. Multiple alleles
Which of the following terms best describe when the phenotype of the hetrozygote differs from the phenotypes of both homozygotes?
A. Incomplete dominance
B. Multiple alleles
C. Pleiotropy
D. Epistasis
A. Incomplete dominance
A relationship between A and B alleles for the ABO blood group is
A. Recessive and dominant
B. Semidominance
C. Codominance
D. Superdomomance
C. Codominance
Which blood types can be found in the children whose both parents have O blood groups?
A. O
B. O and A
C. O, A and AB
D. O, A, AB, B
A. O
Which blood types can be found in the children whose both parents have O blood groups?
A. O
B. O and A
C. O, A and AB
D. O, A, AB, B
A. O
What is the chromosomal system for the sex determination in birds?
A. X-O
B. X-X
C. X-Y
D. Z-W
D. Z-W
What is the chromosomal system of sex determination in most species of ants and bees?
A. Haploid- diploid
B. X-O
C. X-Y
D. Z-W
A. Haploid -diploid
Males are more often affected by sex- linkage trait than female because
A. Males are hemizygous for the X chromosome
B. Female hormones such as oestrogen often compensate for the effects of the mutations on the X
C. X chromosome in males generally have more mutations than X chromosome in female
D. Mutations on the Y chromosome often worsen the effects of X-linked mutations
A. Males are hemizygous for the X chromosome
A Barr body is normally found in the nucleus of which kind of human cell?
A. Unfertilised egg cells only
B. Sperm cells only
C, somatic cells of a female only
D, somatic cells of a male only
C. Somatic cells of a female body only
Barr body is condensed inactivated X Chromosomes
The frequency of crossing over between any two linked genes will be which of the following
A. Higher if they are recessive
B. Dependent on how many alleles there are
C. Determined by their relative dominance
D. Proportional to the distance between them
D. Proportional to the distance between them
Loss of one nucleotide in a dna molecule has generally
A. Milder effect than nucleotide substitution
B. No effect at al
C. Greater effect than nucleotide substitution
D. Lesser consequence than a loss of three nucleotides
C. Greater effect than nucleotide substitution
A cell that has 2n + 1 chromosomes is
A. Trisomic
B. Monosomic
C. Euploid
D. Triploid
A. Trisomic
Women with Turner syndrome have a genotype characterised as which of the following
A. Mental retardation and short arms
B. A karyotype of 45, X
C. A karyotype of 47, XXX
D. A deletion of the Y chromosome
B, a karyotype of 45, X
The frequency of Down syndrome in the human population is most closely correlated with which of the following
A. Frequency of new meiosis
B. Average of the ages of the mother and father
C. Age of the mother
D. Age of the father
C. Age of the mother
A karyotype in Down syndrome is characterised by the presence of an extra copy of genetic material on the
A. Chromosome 21
B. Chromosome 22
C. Chromosome 12
D. Chromosome 18
A. Chromosome 21
Plant species A haas a diploid number of 12. Plant species B has a diploid number of16. A new species C arises as an allopolyploid from A and B. The diploid number for species c would probably be
A. 12
B. 14
C. 16
D. 28
D. 28
Germ cells
A. In humans contain 46 chromosomes
B. Are diploid
C. Contain XX or XY combinations of sex chromosomes
D. Contain half the number of chromosomes of somatic cells
D. Contain half the number of somatic cells
A flagellum composed of micro tubular bundles is responsible for the locomotion of :
A. Bacteriophages
B. Sperm cells
C. Bacteria
D. Amoebae
B. Sperm cells
Parthenogenesis is a form of
A. Sexual reproduction in ciliate Protozoa
B. Sexual reproduction in hermaphrodites
C. Asexual reproduction in which females produce eggs that develop without fertilisation
D. Asexual reproduction in lower organisms by which progeny arises by fragmentation of a parent organism
C. Asexual reproduction in which females produces eggs that develop without fertilisation
Which of following is true for a species that has a chromosome number of 2n = 16
A. The species is diploid with 3w chromosomes per cell
B. The species has 16 sets of chromosomes per cell
C. Each cell has 8 homologous pairs
D. A gamete from this species has 4 chromosomes
C. Each cell has 8 homologous pairs
which of the following happens at the conclusion of meiosis?
a. homologous chromosomes are separated
b. the chromosome number per cell is conserved
c. sister chromatids are separated
d. four daughter cells are formed
a. homologous chromosomes are separated
homologous chromosomes synapse and crossing over occurs
a. the statement is only true for mitosis only
b. the statement is true for meiosis I only
c. the statement is true for meiosis II only
d. the statement is true for mitosis and meiosis
b. the statement is true for meiosis I only
chromatids are separated from each other
a. the statement is true for meiosis I only
b. the statement is true for meiosis II only
c. the statement is true for mitosis and meiosis I
D. the statement is true for mitosis and meiosis II
D. the statement is true for mitosis and meiosis II
the independent assortment of chromosomes occurs
a. the statement is true for mitosis only
b. the statement is true for meiosis I only
c. the statement is true for meiosis II only
d. the statement is true for mitosis and meiosis
b. the statement is true for meiosis I only
a human cell containing 22 autosomes and a Y chromosome is
a. a sperm
b. an egg
c. a zygote
d. a somatic cell
a. a sperm