Multifetal Gestation and Malpresentation (Moulton) Flashcards
__1__ arise when two separate ova are fertilized by two separate sperm.
Each will have its own __2__, __2__, and __2__.
1) Dizygotic twins (Fraternal)
2) Amnion, chorion and placenta
__1__ arise from the cleavage of a single fertilized ovum at various stages during embryogenesis.
Thus the arrangement of __2__ and __2__ will depend on the time at which the embryo divides.
1) Monozygotic Twinning (Identical)
2) Fetal membranes and placentas
With Monozygotic twins, if cleavage takes place from 0-3 days, what happens with placentation? (30% of monozygotic twins have this placentation)
1) 2 chorions
2) 2 amnions
3) Placentas can be separate or fused
With Monozygotic twins, if cleavage takes place from 4-8 days, what happens with placentation? (69% of monozygotic twins have this placentation)
1) 1 chorion
2) 2 amnions
With Monozygotic twins, if cleavage takes place from 9-12 days, what happens with placentation? (1% of monozygotic twins have this placentation)
1) 1 chorion
2) 1 amnion
Monochorionic monoamniotic placentation (9-12 days) is the most dangerous because there are no separating amnions, this causes what risk to be high?
Cord entanglement is high
With Monozygotic twins, if cleavage takes place from 13-15 days, what happens with placentation?
This causes conjoined twins and if they are craniopagus (2% incidence) this means?
If they are thoracopagus (30-40% incidence)?
If they are ischiopagus (6% incidence)?
1) 1 chorion and 1 amnion
2) Joined at the cranium
3) Joined at the chest wall
4) Joined by the coccyx and sacrum
Dizygotic twins is strongly influenced by?
It is twice as common after?
1) Maternal age
2) 35 y/o
You should suspect multiple gestations if ___ is higher than normal.
hCG
Which type of twins have an increased incidence of congenital anomalies, weight discordance, premature delivery, and fetal demise?
Monozygotic
When using US when determining zygosity for dizygotic twins you might see a different __1__ amongst the twins.
There may be visualization of a __2__ septum.
A __3__ sign at the base of septum may be seen.
1) Fetal gender
2) Thick amnion-chorion septum
3) Peak or inverted V
When using US when determining zygosity for monozygotic twins what may be seen?
Dividing membrane is thin
If ultrasound is not definitive in determining zygosity, what should you do?
1) Inspect placenta after delivery
2) DNA analysis
Conjoined twins results do to cleavage occurring at?
13-15 days
With conjoined twins elective termination is an option if what is identified?
Cardiac or cerebral fusion
What has a 90% chance of occurring in monochorionic twins?
The most common type is?
1) Interplacental vascular anastomoses
2) Arterial-arterial
With interplacental vascular anastomoses, vascular communications between the 2 fetuses through the placenta can cause several problems such as?
1) Abortion
2) Polyhydramnios
3) Twin-twin transfusion syndrome (TTTS)
Twin-twin transfusion syndrome results secondary to uncompensated __1__ anastomoses in a monochorionic placenta.
This leads to a net transfer of blood flow going from one twin to the other. Hypovolemia, hypotension, anemia, oligohydramnios, growth restriction occurs to the __2__.
Hypervolemia, polyhydramnios, thrombosis, hypertension, polycythemia, edema, cardiomegaly, and congestive heart failure occurs to the __3__.
1) Arteriovenous
2) Donor twin
3) Recipient twin
With Twin-twin transfusion syndrome both twins are at risk of demise because of?
Heart failure