Contraception and sterilization (Wootton) Flashcards
What provide the most effective reversible contraception?
Hormonal contraceptives
Majority of oral contraceptives are a combination of ____ and ____.
Estrogen and progesterone
Oral contraceptives cause suppression of what hormones?
1) Hypothalamic GnRH
2) Pituitary LH and FSH
The __1__component of the oral contraceptive is the major player by suppressing LH and therefore ovulation as well as thickening cervical mucus, inhibiting sperm migration and creating an unfavorable atrophic endometrium for implantation.
The __2__ component mainly improves cycle control by stabilizing the endometrium and allows less breakthrough bleeding.
1) Progesterone
2) Estrogen
The progestin-only oral contraceptives have a MOA of?
Making cervical mucus thick and impermeable
The progestin-only oral contraceptives is mainly used in __1__ women and women who have a contraindication to __2__.
1) Breastfeeding
2) Estrogen
Some benefits of oral contraceptives include a __1__ menstrual cycle.
They can improve __2__ which is a common side effect of menstruation.
They decrease the risk of __3__ due to shorter and less heavy cycles.
They can lower incidence of __4__ and __4__ cancers.
1) Regular
2) Dysmenorrhea
3) Iron deficiency anemia
4) Endometrial and ovarian
What are side effects seen with oral contraceptives either in the first three months or in the first year?
1) Breakthrough bleeding
2) Amenorrhea
Some serious side effects of oral contraceptives include?
1) Venous thrombosis
2) PE
3) MI
4) Hepatic tumors
The transdermal patch contraceptive has what hormones in it?
There is caution with use in women greater than how many pounds?
Side effects and precautions same as oral contraceptives except for greater risk of?
1) Estrogen and progesterone
2) 198 pounds
3) Thrombosis
The vaginal ring contraceptive has what hormones in it?
Why is it associated with greater compliance?
1) Estrogen and progesterone
2) Because of its once a month use
What is the prescription for the newer vaginal ring, the annovera vaginal ring?
Prescription for 13 months in one reusable ring
For the annovera vaginal ring you place in vagina for __1__ days and remove for __2__ days and then reuse.
1) 21 days
2) 7 days
What populations can not use oral contraceptives?
1) Over 35 and smoke
2) History of thromboembolic event
3) Moderate to severe liver disease
Depot medroxyprogesterone acetate (Depo provera) is given by __1__ every 11-13 weeks.
It maintains contraceptive level of __2__ for about 14 weeks.
Preferred to be given within first 5 days of __3__ and if not use a backup method for 2 weeks.
1) Intramuscular injection
2) Progestin
3) Menses
The MOA of Depot medroxyprogesterone acetate is a thickening of __1__.
Decidualization of the __2__.
It blocks the __3__ and ovulation.
1) Cervical mucus
2) Endometrium
3) LH surge
With Depo-Provera, alterations of ____ metabolism is associated with decreased estrogen levels.
Bone
What side effects are associated with Depo-Provera?
1) Irregular bleeding
2) Weight gain
3) Exacerbation of depression
What implantable hormonal contraceptive is a single, radiopaque, rod-shaped implant containing 68 mg etonogestrel, 4cm long and 2mm in diameter?
It can be used for how many years?
1) Nexplanon (Etonogestrel implant)
2) Three years