mucous membrane Flashcards
What is oral mucosa?
mucous membrane lining the oral cavity and coated by serous and mucous secretions
What does the oral mucous membrane histologically consist of?
- surface epithelium
- CT (lamina propria)
- junction between epithelium CT (basement membrane)
Is there submucosa in the oral mucous membrane?
sometimes
What is found under the hard palate?
maxilla bone
Is there bone under the soft palate?
no
What is the vestibule?
a gap that separates the lip and the mucosa
What are the 2 sides of the tongue called?
- superior surface (dorsum)
- inferior surface (ventral)
What is found under the gingiva?
alveolar mucosa (red coloured area)
What is under the tongue?
floor of the mouth
What covers alveolar bone?
alveolar mucosa
What is the oral mucosa classified into?
- masticatory mucosa (keratinised mucosa)
- lining mucosa (non-keratinised mucosa)
- specialised mucosa
What are the masticatory mucosa?
- hard palate
- gingiva
What are the lining mucosa classified into?
- firmly attached
- loosely attached
What is the firmly attached lining mucosa?
- soft palate
- inferior surface of tongue
- lip
- cheek
What is the loosely attached lining mucosa?
- alveolar mucosa
- vestibular formix
- floor of the mouth
What is the specialised mucosa?
dorsal surface of the tongue
What is the function of the lining mucosa?
protective lining
Why is the alveolar mucosa loosely attached?
to allow movement of the lip
Why is the vestibular formix (oral vestibule) loosely attached?
to allow movement of the cheek
Why is the floor of the mouth loosely attached?
to allow movement of the tongue
All of the gingiva is keratinised, except…
- gingival col
- gingival sulcus
Why is the dorsum of the tongue a specialised type of mucosa?
it contains different types of papillae, taste buds and lingual tonsils
What is the colour of gingiva?
pink and pigmented in coloured races
What is the mucogingival junction (healthy line)?
a scalloped line that separates gingiva from alveolar mucosa
What happens if the healthy line is absent?
there is gingivitis
Where is the healthy line present?
facial aspects of lower and upper jaws, lingual, aspect of lower jaw but not on palatal aspect of upper jaw
What is gingiva divided into?
- free gingiva
- gingival sulcus
- attached gingiva
- inter-dental papilla
What separates free gingiva from the attached gingiva?
free gingival groove
What causes the formation of free gingival groove?
functional impacts upon free gingiva
Where is the free gingiva found?
extends along cervical level of the tooth at labial, buccal and lingual surfaces
Is free gingiva moveable?
yes, it if freely moveable
What is the gingival sulcus?
- shallow groove
- lined by non-keratinised epithelium
- its bottom present at point of separation of attached epithelium from the tooth
What happens if the gingival sulcus is very shallow?
build up calculus and bacteria
What is the depth of gingival sulcus and how is it measured?
- from 0-6mm
- average is 1.8mm
- measured by a periodontal probe
Is attached gingiva moveable?
no
What is attached gingiva?
- attached to cementum or periosteum and extends from the free gingival groove to muco-gingival junction which separates the attached gingiva from alveolar mucosa
- surface shows stippling which is due to functional adaptation to mechanical impacts
has roughness to attach food for masticatory function - stippling correspond to heavier epithelial rete pegs
- depressed between eminencies of sockets forming grooves called inter-dental grooves
What is the cause if there is absence of stippling in attached gingiva?
inflammation
What is inter-dental papilla?
- fills inter-proximal spaces between adjacent teeth below the contact area
- have a tent shape labially and buccally
- wedge shape lingually where the base corresponds to a line connecting the margin of the gingiva at the centre of one tooth to the centre of the next one and the apex tapers to the contact area
What is gingival col?
inter-dental gingival tissue found in depression between two peaks of inter-dental papilla (labial and lingual peaks) and is non-keratinised
What are the epithelial layers of gingiva (microanatomy)?
- stratum basale
- stratum spinosum
- stratum granulosum
- stratum cornium
What are the cells at stratum granulosum capable of?
produce DNA and divide by mitosis to give new cells just sufficient to match those lost by desquamation at surface
What are the type of cells and their number of layers in stratum basal?
one layer of high cuboidal (or columnar) cells
The basal cells are connected to each other by…
desmosomes
basal cells are connected to the basement membrane by…
hemidesmosomes
What are rete pegs?
- down growth of epithelium to C.T.
- they interdigitate with C.T. papillae
What are the rete pegs of the gingiva like?
- irregular
- tall
- thin (slender)
- numerous
What are the shape o cells in stratum spinosum?
polyhedral shaped cells (small with wide intercellular spaces)
What are the cells found in stratum granulosum?
- flat cells
- cells contain basophilic granules called keratohyaline granules
- small nucleus
What is the cornfield layer formed of?
keratinised squamae which are larger and flatter than granular cells
What are the types of gingival epithelium according to type of keratinisation?
- orthkeratinised epithelium 15% (where the nuclei and other organelles disappeared)
- parakeratinised epithelium 75% (sratum corneum retains pyknotic nucleus or remnants of nuclear material (cell organelles))
- non-keratinised epithelium 10% (stratum corneum is absent)
Where is non-keratinised epithelium foundin gingiva?
- gingival sulcus
- gingival col
What are keratinocytes?
cells found in stratum basale, stratum granulosum and stratum spinosum
Wat are the functions of keratinocytes?
make keratin when needed
What does the reticular layer contain?
collagen fibers arrangd in a loose network with free agirophilic fibers
What does the deep layer contain?
dense collagen fibers arranged in network
What do the desmosomes consist of?
- thickening of adjacent cell membrane (2 adjacent cells)
- a pair of attachment plaque (2 adjacent cells)
- tonofilaments
- extracellular structure (act as glue)
What are found in hemidesmosomes?
- lamina densa
- basal lamina
- anchoring fibril
- lamina lucida
- reticular fibers (lamina)
What do hemidesmosomes consist of?
- thickening of cell membrane
- tonofilaments
- extracellular structure
- single attachment plaque
Are the cells in stratum spinosum protein forming cells?
yes
What are odland’s bodies?
- other name: keratinosomes
- membrane coating granules
- present in superficial layer of spinous cell layer or in lower granular cell layer
- have internal lamellated structure
- originate from golgi system
- responsible for thickening of cell membrane which occurs during keratinisation
- may form an intercellular agglutinating material
What is filaggrin?
protein of keratohyaline granules (matrix between keratin around tonofilaments
What are non- keratinocytes?
- pigment cells
- langerhams cells
- merkel cells
- inflammatory cells
What are pigment cells and their characteristics?
- melanocyte or melanoblast
- found in basal and para basal cell layer
- pigmentation ranges from light brown to black present as granules in the cytoplasm of the cells
- cells are derived from neural crest cells
- cells are larger than epithelial cells and they send large branched process in intercellular spaces of other keratinocytes
Where does pigmentation of gingiva occur mostly?
attached gingiva beneath inter-dental papilla
By electron microscope, what do melanocytes lack?
tonofilaments and desmosomes