Mucorales Flashcards
common environmental isolates associated with soil and plants.
mucorales
contaminate grains, breads, and fruits and are most often associated with infections of the sinuses, lungs, and skin of immunocompromised patients
mucorales
Diabetes is a significant risk factor for these infections.
mucorales
Mucorales infection is comprises of different groups or fungi:
- Cunninghamella
- Lichtheimia
- Mucor
- Rhizopus
- Syncephalastrum
can be recovered from the sinuses or other organs during disseminated disease
cunninghamella
Sporangiophores are erect, branching into several vesicles that bear sporangioles, and may be covered with long, fine spines.
cunninghamella
rapidly growing and form a cottony colony that is initially white but becomes gray with age.
cunninghamella
have a predilection for vascular invasion, causing thrombosis and necrosis of the tissues.
lichtheimia
usually found in patients with diabetes and ketoacidosis.
lichtheimia
rhizopus
In this patient population, the infection usually begins in the sinuses, where conidia are inhaled and take up residence.
Lichtheimia
From the sinuses, infection rapidly spreads to the orbits, face, palate, and brain.
rhinocerebral mucormycosis.
are found worldwide and are often associated with soil or decomposing organic matter
lichtheimia
Erect sporangiophores, solitary or in groups (slightly branched), terminate in an apophysis surrounded by a sporangium.
lichtheimia
short, thin projections that anchor the growing cells to substratum
internal rhizoids
Colonies are woolly and grow rapidly, completely covering the culture medium.
rhizopus. lichtheimia
have been implicated in rhinocerebral mucormycosis in addition to disseminated disease.
mucor
Sporangiospores are formed in sporangia on erect sporangiophores
mucor
grow rapidly and form cottony, dirty white colonies that become mousy brown to gray with age.
mucor
may be refractory to treatment and may be recovered from almost any source. With worldwide distribution, this isolate is easily recovered from the environment in decaying vegetation.
rhizopus
The sporangia are typically fragile and are not easily retained when making slide culture preparations, resulting in an umbrella-shaped structure at the end of the conidiophores.
mucor
Colonies are initially white but become gray to brown with age
rhizopus
rarely implicated in human disease but has been documented in cutaneous infections.
syncephalastum
This fungus is found in soil and decaying vegetation.
syncephalastum
Isolates are sometimes confused with Aspergillus on initial examination
syncephalastum
Each sporangiophore has a large columella on which merosporangia, containing stacks of sporangiospores, are formed
syncephalastum
Colonies are rapidly growing and are initially white and become gray with age.
The growth rate is rapid, with colonies covering the entire surface of the agar.
syncephalastum