MSRA: Thyroid Disease

Question 1

Which antibodies are associated with Grave’s disease?

Answer 1

TSH receptor antibodies (TRAB)

Question 2

Which antibodies are associated with Hashimoto’s disease?

Answer 2

Thyroid peroxidase antibodies

Thyroglobulin antibodies

Question 3

What is meant by De Quervain’s thyroiditis?

Answer 3

Inflammation of the thyroid gland following a viral infection.
Painful goitre with raised ESR
Self-limiting

Question 4

What are the features of sick euthyroid syndrome?

Answer 4

Normal TSH
Low T4
Acute illness

Question 5

What are the contraindications for radioactive iodine?

Answer 5

Pregnancy
Unstable Grave’s eye disease

Question 6

What are the features of Riedel’s thyroiditis?

Answer 6

Painless ‘woody’ goitre

Question 7

Which medication reduces the absorption if taking alongside Levothyroxine?

Answer 7

Iron tablets

Question 8

What are the side effects of Carbimazole?

Answer 8

Agranulocytosis

Question 9

What is the management of subclinical hypothyroidism

Answer 9

If TSH > 10 - Levo
If symptomatic and TSH 5.5-10 - Levo trial