MSRA: TB Flashcards

1
Q

What is the antimicrobial management of TB?

A

Rifampicin and Isoniazid for 6 months
Pyrazinamide and Ethambutol for 2 months

Pyridoxine (vitamin B6) alongside Isoniazid

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2
Q

What are the side effects of Rifampicin?

A

Hepatitis
Orange/red discolouration of body fluids
CYP inducer

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3
Q

What are the side effects of Isoniazid?

A

Hepatitis, rash, peripheral neuropathy, CYP inhibitor

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4
Q

What are the side effects of Pyrazinamide?

A

Hepatitis, gout

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5
Q

What are the side effects of Ethambutol?

A

Optic neuritis

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6
Q

Name two medications associated with TB re-activation

A

Steroids
anti-TNF alphas (Biologics) eg Infliximab

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7
Q

What is the management of meningeal TB?

A

RIPE for 2 months
Rifampicin and Isoniazid continued for a further 10 months
Dexamethasone or Prednisolone

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8
Q

What is the management of latent TB?

A

Rifampicin and Isoniazid for 3 months or
Isoniazid for 6 months

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