MSRA: TB Flashcards
What is the antimicrobial management of TB?
Rifampicin and Isoniazid for 6 months
Pyrazinamide and Ethambutol for 2 months
Pyridoxine (vitamin B6) alongside Isoniazid
What are the side effects of Rifampicin?
Hepatitis
Orange/red discolouration of body fluids
CYP inducer
What are the side effects of Isoniazid?
Hepatitis, rash, peripheral neuropathy, CYP inhibitor
What are the side effects of Pyrazinamide?
Hepatitis, gout
What are the side effects of Ethambutol?
Optic neuritis
Name two medications associated with TB re-activation
Steroids
anti-TNF alphas (Biologics) eg Infliximab
What is the management of meningeal TB?
RIPE for 2 months
Rifampicin and Isoniazid continued for a further 10 months
Dexamethasone or Prednisolone
What is the management of latent TB?
Rifampicin and Isoniazid for 3 months or
Isoniazid for 6 months