MSRA - Infectious Diseases Flashcards
Campylobacter jejuni features
- Flu-like prodrome
- Crampy abdo pains may mimic appendicitis
- Diarrhoea may be bloody
- Complications: GB syndrome
Hepatitis c incubation period
6-9 weeks
Hepatitis C and breastfeeding
Allowed
Hepatitis C serology: anti-HCV
Previous hepatitis C infection.
Persists even if cleared virus
Hepatitis C serology: HCV RNA
Acute infection
If present >6 months = chronic hepatitis C
Management of hepatitis C
Protease inhibitors +/- ribavirin
Ribavirin side effects
Haemolytic anaemia
Cough
Teratogenic (stop 6m before getting pregnant)
IFN-a side effects
Flu-like symptoms
Depression
Fatigue
Leukopenia/thrombocytopenia
Treatment of confirmed Lyme disease: early disease
Doxycycline
Amoxicillin in pregnancy
Treatment of confirmed Lyme disease: disseminated disease
Ceftriaxone
Amsel’s criteria for diagnosis of BV
3 out of 4 of:
- Thin, white homogenous discharge
- Clue cells
- pH > 4.5
- Positive whiff test (potassium hydroxide)
Management of bacterial vaginosis
oral metronidazole 5-7 days
Chlamydia trachomatis incubation period
7-21 days
Chlamydia - when to test
2 weeks after possible exposure
Management of chlarmydia
Azithromycin single dose
OR
Doxycycline 7 days
Management of chlamydia in pregnancy
azithromycin, erythromycin or amoxicillin
Chlamydia contact tracing: men with urethral symptoms
All contacts from four weeks prior to symptom onset
Chlamydia contact tracing: asymptomatic men
All partners from last six months
Chlamydia contact tracing: women
All partners from last six months
Treatment of active tuberculosis
Initial phase - 2 months of RIPE
Continuation phase - 4 months of RI
Treatment of latent tuberculosis
3 months of isoniazid (+ pyridoxine) and rifampicin
OR
6 months of isoniazid (with pyridoxine)
Treatment of meningeal tuberculosis
Treat for 12 months, with addition of steroids
Childhood flu vaccine - when given?
First dose at 2-3 years
Annually thereafter
Neisseria gonorrhoeae incubation period
2-5 days
Management of gonorrhoeae
IM ceftriaxone 1g
or oral ciprofloxacin 500mg stat, if known to be sensitive
Commonest causes of acute food poisoning
- Staph aureus
- Bacillus cereus
- Clostridium perfringens
Giardiasis infection presentation
Prolonged, non-bloody diarrhoea
Shigella presentation
Bloody diarrhoea
Vomiting & abdominal pain
Staph aureus food poisoning presentation
Severe vomiting
Short incubation period
Bacillus cereus presentation
Two types:
- Vomiting within 6 hours, due to rice
- Diarrhoeal illness after 6 hours
Amoebiasis presentation
Gradual onset bloody diarrhoea
Abdominal pain and tenderness
May last several weeks
Gastroenteritis: infections with 1-6hr incubation period
Staph aureus
Bacillus cereus
Gastroenteritis: infections with 112-48hr incubation period
Salmonella
E.coli
Gastroenteritis: infections with 148-72hr incubation period
Shigella
Campylobacter
Gastroenteritis: infections with incubation period >7 days
Giardiasis
Amoebiasis
Herpes in pregnancy: primary attack >28 weeks
Elective caesarean section
Trichomonas vaginalis features
- offensive frothy vaginal discharge
- vulvovaginitis
- strawberyy cervix
- pH >4.5
Management of trichomonas vaginalis
Oral metronidazole