MSRA: Anti-Depressants

Question 1

What are the side effects of SSRIs?

Answer 1

GI disturbances
Increased suicidal ideation
Hyponatraemia
Risk of GI bleeding

Question 2

What are the side effects of TCAs?

Answer 2

Dry mouth
Urinary retention
Blurred vision

Question 3

What are the adverse effects of mirtazapine?

Answer 3

More sedating at lower doses
Drowsiness
Increased appetite

Question 4

What is the SSRI of choice in CAMHS?

Answer 4

Fluoxetine

Question 5

How can we manage the bleeding risk associated with SSRIs?

Answer 5

To take PPI if also taking NSAID or Aspirin
If taking Warfarin, consider alternative such as Mirtazepine

Question 6

Which SSRI has the higher incidence of discontinuation symptoms?

Answer 6

Paroxetine

Question 7

What are the features of SSRI discontinuation syndrome?

Answer 7

Dizziness/lightheadedness
Paraesthesia
Insomnia
GI disturbances

Question 8

What are the features of serotonin syndrome?

Answer 8

Confusion
Agitation
Muscle twitching
Sweating

Question 9

Name one specific side effect of Citalopram?

Answer 9

Prolonged QT interval

Question 10

Which SSRI is of choice following MI?

Answer 10

Sertraline

Question 11

After starting SSRI, when should patients <25 be reviewed?

Answer 11

After 1 week