MSK Y2 Flashcards
Osteochrondroma
- Benign
- bony outgrowth with cartilagenous cap
- local pain
Surgical removal
Endochondroma
- Benign
- intramedullary and metaphyseal cartilaginous tumour caused by failure of normal enchondral ossification
Curettage + bone graft
Simple Bone cyst
- benign
- asymptomatic, found on proximal humerus and femur.
Curettage + bone graft
Osteoid Osteoma
- benign
- small collection of immature bone surrounded by an intense sclerotic halo
- constant pain, worse at night
Self-resolving
NSAIDS
CT guided radiofrequency ablation
Brodie’s Abscess
- benign
- subacute osteomyelitis
Currettage
Osteosarcoma
- most common malignant bone tumour
- produces bone
- in knees of young patients
Chemotherapy
Ewings Sarcoma
- malignant tumour of primitive cells in the marrow
- “onion skin” appearance on XR
- fever, warm swelling, raised inflammatory markers
- common in teens
- chromosome 22, EWS gene
Radiotherapy
Chemotherapy
Surgery
Osteogenesis Imperfecta
- brittle bone disease
- blue sclera
- multiple fractures
- defect of type 1 collagen
- loss of hearing
Splintage
Traction
Stabilisation (Sofield procedure)
Achondroplasia
- short stature
- prominent forehead
- widened nose
- lax joints
- normal mental IQ
Deformity correction
Limb lengthening
Growth hormone therapy
Ehler-Danlos Syndrome
- abnormal elastic and collagen formation
- hypermobility
- vascular fragility (easily bruised)
Surgery (for dislocating joints)
Duchenne Muscular Dystrophy
- progressive muscle weakness in boys
- trendelenburg positive + Gowers sign positive
- resp and cardio failure related death in 20s
- raised CK
- X linked, dystrophin gene- calcium linked
Physiotherapy
Splintage and deformity correction
Surgery (for scoliosis)
Beckers Muscular Dystrophy
- similar to DMD but live into their 40s
Physiotherapy
Splintage and deformity correction
Surgery (for scoliosis)
Erb’s Palsy
- obstetric injury
- waiters tip posture
- C5-6 nerves
- associated with scoliosis, ptosis and horners syndrome
Physiotherapy
Nerve transfer
Subscapularis releases
Latissimus Dorsi Tendon Transfers
Klumpke’s Paralysis
- C8-T1 nerves
- paralysis of forearm and hand muscles
Physiotherapy
Developmental Dysplasia of the Hip (DDH)
- perinatal dislocation of the hip
- shortened limb
Pavlik Harness
Transient Synovitis
- inflammation of the synovium of a joint following a viral infection
Self-limiting
Rest + NSAIDS
Perthes Disease (Legg-Calvé-Perthes)
- idiopathic osteochondritis of the femoral head
- age 4-9, commonly boys
- pain, limb, Trendelenburg positive
- AVN of femoral head
Self-healing (18+ months)
NSAIDS
Physiotherapy (Swimming etc)
If non-healing: Osteotomy
Sipped Upper Femoral Epiphysis (SUFE)
- inferiorly slipped neck of femur due to growth plate not being able to cope with weight
- pain in knee, groin
- loss of internal rotation
Immediate internal fixation in-situ using screws to prevent slippage
Chronic slipping: Osteotomy
Talipes Equinovarus (Club Foot)
- feet are rotated medially and inferiorly
- congenital deformity
Ponseti technique splintage (4-6 week blocks)
Shoulder Impingement Syndrome
- tendons of the rotator cuff are compressed in the tight subacromial space during movement
- pain between 60-120 degrees on extension
NSAIDS, Analgesia, Physiotherapy
Subacromial steroid injection
Subacromial decompression
Tarsal Coalition
- abnormal bridge between calcaneus, navicular and talus
Splintage
Resistant: Surgery to remove connection
Rotator Cuff Tear
- pain and weakness in shoulder muscles
Surgery
Physiotherapy
Adhesive Capsulitis (Frozen Shoulder)
- pain and stiffness of shoulder between 40-60 degrees on abduction
- loss of external rotation
Self-limiting (18-24months)
Physiotherapy + NSAIDS
Steroid injections
MUA (Manipulation under anaesthetic)
Medial Epicondylitis (Golfer's Elbow) - painful and tender on flexion
Rest + NSAIDs
Steroid injection
Brace
Lateral Epicondylitis (Tennis Elbow) - painful and tender on extension
Rest + NSAIDs
Steroid injection
Brace
Tendonitis
- inflammation of a tendon
Self-limiting
Steroid/ anaesthetic injection
Torn tendon of biceps (Popeye’s deformity)
Self-healing
Rest
Sometimes: surgical repair
Dupuytren’s Contracture
- proliferation of type 3 collagen fibres
- begins in palm, works outwards
- thickens tendons in palm
- ring finger is most common
- common in alcoholics, Peyronie’s disease and diabetics
Fasciectomy
Fasciotomy
Needle aponeurotomy
Amputation of finger(s)
30 degrees is tolerated
Table top test= positive= treatment
Trigger Finger
- tendonitis of flexor tendon with nodular enlargement
- gets caught on A1 pulley
- clicking sensation on straightening finger
- 3rd/4th digit
Steroid injection
Surgery
Ganglion Cyst
- cyst at synovial joint
- transilluminates
Recurrent: Aspiration/ excision
Trochanteric Bursitis
- inflammation of a bursae at a joint
- caused by over activity
Rest, analgesia, NSAIDS, Physiotherapy
Anterior Cruciate Ligament Rupture
- painful sports injury
- twisting movement on planted feet with “pop”
- instant haemarthrosis and swelling
- positive Lachman’s test and anterior drawer test
ACL reconstruction/ tendon graft (using patellar tendon)
Rehab
1 year out of sport
Posterior Cruciate Ligament Rupture
- head on blow to the shin
- instability on going down stairs
- doesn’t swell as much as ACL
- posterior sublaxation of the tibia, positive posterior drawer test
Reconstruction
De Quervain’s Tenosynovitis
- spontaneous swelling and pain in the thumb
- common in middle-aged women, RA and pregnancy
NSAIDS
Splint/ rest
Steroid injection
Decompression surgery
Medial Collateral Ligament Rupture
- pain on medial stress
Knee brace
Lateral Collateral Ligament Rupture
- pain on lateral stress
- more unstable than MCL
Reconstruction
Patellar Instability
- due to direct blow/ twist
- usually dislocated laterally
- spontaneous reduction
Physiotherapy to strengthen quadriceps
Recurrent: Surgery and reconstructed medial palatofemoral ligament
Compartment Syndrome
- internal bleeding and exudate from fracture and injury
- rise in internal pressure
- compression of the venous system, causing congestion within muscle
- secondary ischaemia as arterial blood cannot supply the congested muscle
- severe pain
- nerves are compressed resulting in parasthesia and sensory loss
Emergency fasciotomy
Giant Cell Tumour
- benign
- locally destructive
- around knee and distal radius
- multinucleated giant cells
- “soap bubble” appearance on XR
Excision
Phenol/ bone cement/ liquid nitrogen
Fibrous Dysplasia
- common in adolescents, head and neck
- defective mineralisation
- affected bone is wider with thin cortices, can stress fracture
- shepherd’s crook deformity in the proximal femur
Biphosphonates- reduce pain
ORIF + cortical graft
High recurrence: Excision
Chondrosarcoma
- malignant
- cartilage producing bone tumour
- in their 40s, pelvis and femur
Surgery
Doesn’t respond to chemo/radio therapy
Myeloma
- a type of cancer that develops from cells in the bone marrow called plasma cells
- age 45-65
- recurrent infection
- deposition of AL amyloid
- weakness, back pain, bone pain,
Solitary plasmacytoma: radiotherapy
Multiple myeloma: chemotherapy
Lipoma
- a benign neoplastic proliferation of fat
Excision
Baker’s Cyst
- swelling of synovial fluid in the popliteal
Leave alone
Recurrence: Excision
Abscess
- cellulitis in wound / blocked sweat gland / cyst
Self-limiting
Incision + drainage
Implantation Dermoid
- Epithelial Cells in subcutaneous tissue
- Cyst with pseudocapsule and grey fluid
Excision
Angiosarcoma
- Malignant tumour of the blood vessels
Chemotherapy: Doxorubicin
Surgery
Osteochondritis
- An area of bone that has lost blood supply leading to cartilage chipping off
Detaching cartilage: Pin back in place
Detached: Fix or remove
Sometimes spontaneously self-heals
Avascular Necrosis
Drilling into the bone to decompress it
Osteoporosis
- Vitamin D, Calcium, weight bearing exercises, balanced diet, sun exposure
- Biphosphonates (alendronate, risedronate, etidronate)
- Desuromab
- Strontium
Post-menopause: Raloxifene
Annual Zoledronic injection (biphosphate)
Osteomalacia
- Vitamin D, Calcium, weight bearing exercises, balanced diet, sun exposure
- Biphosphonates (alendronate, risedronate, etidronate)
Paget’s Disease
- Biphosphonates (alendronate, risedronate, etidronate)
- Calcitonin
IPEX Syndrome
Extremely prone to infections
Supportive
Immunosuppressants
Total parental nutrition
Osteoarthritis
- Loss of joint space
- Osteophytes
- Sclerosis (hardening of bone)
- Subchondral cysts
Analgesia + NSAIDS
Opiates + intraarticular steroids (short term)
Physiotherapy + occupational therapy + weight loss
Glucosamine phosphate supplement
Joint replacement
Osteoarthritis of hands/fingers
- PIP and DIP joints
- Base of thumb
- Heberden’s nodes
- Bouchard’s nodes
Analgesia + NSAIDS
Opiates + intraarticular steroids (short term)
Physiotherapy + occupational therapy + weight loss
Glucosamine phosphate supplement
Fusion of joints
Rheumatoid Arthritis
- MCP + PIP joints
- Swan neck deformity
- Boutonniere’s deformity
DAS28 Score: <2.6: remission 2.7-3.2: Low disease activity 3.3-5.1: Moderate >5.1: High
Patients with newly diagnosed active RA start a combination of DMARDs (including methotrexate and at least one other DMARD, plus short-term glucocorticoids.
Short term: Analgesia, NSAIDS, Steroids (injection/oral)
Long term:
- DMARDS (methotrexate, sulphasalazine, hydroxychloroquine, leflunomide)
If >5.1 DAS28 Score
- Anti-TNFs (etanercept, infliximab, adalimumab)
- Biologics (rituximab, abatacept)
Ankylosing Spondylitis
- chronic inflammation of the spine and sacroiliac joints
Physiotherapy + exercise
NSAIDS
Anti-TNF
Psoriatic Arthritis
Methotrexate
Doesn’t respond: Anti-TNF
Still severe: Joint replacement/ fusion
Enteropathic Arthritis (IBD Arthritis)
Analgesia
Steroids
DMARDS
Anti-TNF (Infliximab, adalimumab)
Reactive Arthritis
- In response to infection (usually genitourinary)
- Associates with Reiter’s syndrome
Self-limiting
Treat underlying disease
Steroids (injection)
Chronic: DMARDS
Systemic lupus erythematosus (SLE)
- Systemic autoimmune disease
- Type III hypersensitivity
Skin and arthralgia: hydroxychloroquine, topical steroids + NSAIDS
Inflammatory arthritis/ organ involvement: Azathioprine, mycophenolate, corticosteroids
Severe organ disease: IV Steroids/ cyclophosphamide
Unresponsive cases: IV Ig, rituximab
Sjogren’s Syndrome
Lubricating eye drops Dental care Pilocarpine Hydroxychloroquine DMARDS
Systemic Sclerosis
Raynauds: CCBS, iloprost, bosentan
Renal: ACE inhibitors
GI: PPIs
ILD: DMARDS + cyclophosphamide
Anti-phospholipid Syndrome
Warfarin
LMWH
Gout
Acute:
- NSAIDS (indomethacin)
- corticosteroids, opiate analgesia
- Colchicine
Recurrent/ presence of gout tophi: Alluprinol
Pseudogout
Calcium pyrophosphate dihydrate (CPPD)
Acute: NSAIDS, Colchicine
Recurring: Hydroxychloroquine, methotrexate
Polymyalgia Rheumatics
- myalgia of hip and shoulder of elderly
Prednisolone
Screen for GCA
Giant Cell Arteritis
- Large Cell Vasculitis
- Transmural inflammation of arteries
- > 50 year olds
- Multinucleated giant cells
- Visual problems, headaches, jaw claudication, scalp tenderness
Prednisolone
Methotrexate/ azathioprine
Dermatomyositis
- V-shaped rash over chest
- Heliotrope rash
- Gottron’s papules
Prednisolone
Methotrexate/ azathioprine
Polymyositis
- symmetrical proximal muscle weakness “trouble climbing stairs”
Prednisolone (slow response)
Methotrexate/ azathioprine
Fibromyalgia
- widespread muscle pain + fatigue
- Associated with RA (25% have FM) and SLE (50% have FM)
Self-management therapy
Amitriptyline
Gabapentin
Pregabalin
Takayasu Arteritis
- Large cell arteritis
Prednisolone
Methotrexate/ azathioprine
Granulomatosis with polyangitis
(Wegner’s)
- ANCA Associated Small Vessel Vasculitis
- ENT symptoms (epitaxis, deafness, sinusitis, nose collapse)
- Resp symptoms (haemoptysis, cavitating lesions)
IV steroids + cylophosmamide
Eosinophilic granulomatosis with polyangitis
(Churgg-Strauss Syndrome)
- ANCA Associated Small Vessel Vasculitis
- late onset asthma
- increased eosinophils in blood
- mononeuritis multiplex
IV steroids + cylophosmamide
Microscopic Polyangitis
- ANCA Associated Small Vessel Vasculitis
- causes glomerulonephritis
IV steroids + cylophosmamide
Henoch-Schonlein purpura
- Non-ANCA Associated Small Vessel Vasculitis
- a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children
- the disease causes palpable purpura (small, raised areas of bleeding underneath the skin), often with joint pain and abdominal pain
- kidney involvement
- following an infection
Self-limiting
Cerebral Palsy
Spastic: Damage to motor cortex, upper motorneurons or corticospinal tract. Causing: weakness and spasticity.
Ataxis: Damage to the cerebellum. Reduces co-ordinatino and balance.
Athetoid: Damage to pyramidal motor system, pyramidial tract, and basal ganglion. Causes writhing and speech difficulty.
Physiotherapy + splintage Baclofen injection into subacromial space Botox injection to spastic muscles Rhizotomy Surgical release and fusion of joints
Spina Bifida
- 2 halves of the posterior vertebral arch fail to fuse
- Spina bifida occulta: Mild- high arched foot/toe claws/ back dimple with tuft of hair
- Spina bifida cystica: Severe- herniation of meninges. If myelomeningocele, there may be a neurological deficit. Below region will not function properly.
Cannot cure nerve damage
Closed within 48 hours- surgery
Shunt to reduce hydrocephalus
Systemic evaluation
Polio
- Viral infection that affects the anterior motor horn cells in spinal cord
- Enters via GI tract
- Muscle paralysis in limbs within 2-3 days (sensation is preserved)
Residual paralysis: Splintage
Shortened limb: Shoe raise
Paralysis: Tendon transfers/ fusion
Internal Tibial Torsion
Self resolves by age 6
Metatarsus Adductus
- front half of the foot turns inwards
Self resolves
Casting may help
Femoral Neck Anteversion
Of no consequence- leave be
Genu Varum
Leave be
Osteotomy
Genu Valgus
Leave be
If young and severe: growth plate manipulation surgery
In-toeing
Due to:
- femoral neck anteversion
- internal tibial torsion
Self-resolving
Pes Planus (Flat feet)
Flexible: tibialis posterior tendon dysfunction, normal in kids
Rigid: tarsal coalition
No treatment needed
Patellar tendonitis
Self-limiting
Apophysitis
- inflammation of tubercle where tendon attaches
Osgood-Schlatter’s disease: tibial tuberosity
Sindig-Larsen-Johansson syndrom: inferior pole of the patella
Self-limiting
Rest and physiotherapy
Adolescent knee paint
Self-limiting
Physiotherapy
Osteochondritis dissectans
- Hyaline cartilage broken off at a joint
Leave or remove fragments
Scoliosis
- lateral curvature of the spine
Mild: leave
Severe: Surgery
Spondylolisthesis
- slippage of vertebrae over one another
- L4/5/S1
- overweight adolescents
- lower back pain
Minor degree of slippage: rest + physiotherapy
Severe: stabilization + reduction
Mechanical back pain
Analgesia + physiotherapy
Return to work (no bed rest)
Self resolving
Sciatica
- disc tear
- impingement of nerve roots
- L4/5/S1
Gabapentin
Maintaining mobility
Physiotherapy
Discectomy
Spinal stenosis
- multiple nerve entrapment
- burning pain in legs on walking
Physiotherapy and weight loss
Surgery- decompress + increase space
Cauda Equina Syndrome
Emergency surgical decompression
Carpal Tunnel Syndrome
- median nerve
- paraesthesia in thumb and radial 2.5 fingers
Splints to reduce flexion
Corticosteroid
Surgical decompression- disection of transverce carpal ligament
Cubital Tunnel Syndrome
- ulnar nerve
- paraesthesia in little finger and 1/2 ring finger
Surgical release
Knee arthritis
Isolated OA: unicompartmental knee replacement
Severe: TKR
Meniscal tears
Steroid injection
Self-resolving
Ankle Arthritis
Cheilectomy (removal of osteophytes causing impingement)
Elderly: Ankle prosthesis
Hallux Valgus
- lateral deviation of big toe
Cheilectomy
Arthrodesis
Mortons neuroma
Insoles
Steroid/ anaesthetic injection
Excision if continued pain
Achilles Tendonitis
Rest, physiotherapy
Self-limiting
DO NOT USE STEROIDS- Causes rupture
Achilles Tendon Rupture
Surgical repair and 8 weeks in cast
Plantar Fascitis
- pain on walking
- due to stress on aponeurosis
Rest Stretching exercises Corticosteroid injection Surgical release of plantar fascia Self-limiting
Tibialis posterior tendon dysfunction
Medial arch support
Tendonectomy
Pes Cavus (High arch foot)
Soft tissue release
Tendon transfer
Calcaneal osteotomy
Arthrodesis
Claw Toes
- hyperextension of MTP and hyperfelxion of PIP and DIP
Tenotomy
Tendon transfer
Arthrodesis of PIP
Amputation
Hammer Toes
- hyperextension at MTP, hyperflexion at PIP, hyperextension at DIP
Tenotomy
Tendon transfer
Arthrodesis of PIP
Amputation
Tetanus
- spastic paralysis due to neurotoxin
Surgical debridement
Antitoxin
Supportive measures
Neuropraxia
- nerve conduction block/ demyelination due to compression or stretch
Self healing (28 days)
Axonotmesis
- Death of axons distal to injury (Wallerian degeneration)
Self-healing (1 month)
1mm per day
Neurotmesis
- transection of nerve
No recovery unless surgical repair
Complex Regional Pain Syndrome (CRPS)
- heightened chronic pain syndrome after injury
Analgesia Amitriptyline Gabapentin Steroids Physiotherapy Lidocaine
Soft tissue injury
RICE
Rest
Ice
Compression
Elevation
Aneurysmal bone cyst
- benign
- painful, filled with blood, multiple bones, local destruction and cortical expansion
Curettage + bone graft
Paget’s
- hearing loss
- skull
- back pain
Biphosphonates:
- tiludronate
- aldronate