MSK/ rheumatology drugs Flashcards

1
Q

used in severe lupus / lupus nephritis

A

IV cyclophosphamide

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2
Q

pyridostigmine

A

AChE inhibitor
used for myasthenia graves

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3
Q

used in myasthenia graves crisis?

A

IV immunoglobulin

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4
Q

ACUTE tx for gout

A

NSAIDs
colchicine
steroids

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5
Q

prevention of further gout attacks?

A

allopurinol
febuxostat

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6
Q

calcium pyrophosphate?

A

pseudogout

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7
Q

bisphosphonates mechanism of action?

A

eaten by osteoclasts
induce apoptosis
less bone resorbed

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8
Q

CK elevated?

A

polymyositis

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9
Q

ESR raised?

A

polymyalgia rheumatica

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10
Q

treatment for pagets

A

bisphosphonates + calcitonin

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11
Q

calcitonin function?

A

inhibits osteoclasts
opposite of PTH

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12
Q

colchicine

A

inhibits microtubule formation in macrophages
decreases inflammation signals

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13
Q
A
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