MSK Medications

Question 1

Disease-modifying Antirheumatic Agents

Answer 1

Slow or halt the progression of rheumatic disease

Inhibiting immune response responsible for rheumatic disease

Therapists should recognize that many of the agents have a high incidence of toxicity

Question 2

Glucocorticoid Agents (Corticosteroids)

Answer 2

Reduce inflammation in chronic conditions

Can cause muscle atrophy

Drug-induced Cushing syndrome can also occur

Can cause weakening with breakdown of supporting tissues

A PT needs to wear a mask because of the compromised immune system

Therapist must be aware of signs of toxicity including moon face, buffalo hump, and personality changes.

Question 3

Nonopioid Agents

Answer 3

Provides pain relief, produce anti-inflammatory effects and reduces fever

Masked pain

Complaints of stomach pain should be taken seriously

Tylenol, NSAIDS, Aspirin, Aleve, Advil and Celebrex

Question 4

Opioid Agents (Narcotics)

Answer 4

Provide pain relief for acute severe pain management

Stimulates opioid receptors within the CNS to prevent pain impulses from reaching their destination

Side effects: mood swings, sedation, confusion, etc.

PT should monitor for signs of respiratory depression

Treatment should be done after 2 hours ingesting opioid