MSK Cortex Pathology - Other

Question 1

What is the most common benign soft tissue tumour?

Answer 1

Lipoma (a neoplastic proliferation of fat)

Question 2

How does a giant cell tumour typically present and where?

Answer 2

Small firm swelling on the flexor tendon sheath of a finger. (may be painful)

Question 3

What do giant cell tumour of tendon sheaths histologically contain?

Answer 3

Multinucleated giant cells and haemosiderin

Question 4

Malignant soft tissue tumours arising from the connective tissue are known as what?

Answer 4

Sarcomas

Question 5

What is a ganglion?

Answer 5

A fluid filled lump associated with a join or tendon sheath

Question 6

Which conditions may cause avascular necrosis (AVN)?

Answer 6

1. Thrombophilia
2. Sickle cell disease
3. Antiphospholipid deficiency in SLE

Question 7

What is Caisson’s disease and how can it cause AVN?

Answer 7

Decompression sickness (“the bends”) - causes AVN from nitrogen bubbles forming in the circulation after too rapid a depressurisation after deep sea diving