MSK Cortex Pathology - Benign bone tumours Flashcards

1
Q

What is the commonest benign bone tumour?

A

Osteochondroma

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2
Q

Describe an osteochondroma?

A

A bony outgrowth on the external surface with a cartilaginous cap

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3
Q

Describe a enchondroma?

A

An intramedullary and usually metaphysical cartilaginous tumour caused by failure of normal enchondral ossification at the growth plate

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4
Q

Describe a simple bone cyst?

A

A single cavity benign fluid filled cyst in a bone

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5
Q

Where are simple bone cysts usually found?

A

Metaphysis of long bones (usually in the proximal humerus and femur) most commonly found in children

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6
Q

Describe an aneurysmal bone cyst?

A

Cyst containing lots of chambers which are filled with blood or serum

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7
Q

What benign bone tumour has a characteristic “soup bubble” appearance on x-ray?

A

Giant cell tumour

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8
Q

Where are giant cell tumours usually found?

A

Around the knee and in the distal radius but can occur in other long bones, pelvis and spine

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9
Q

5% of giant cell tumours can metastasise to where?

A

The lung

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10
Q

Shepherd’s crook deformity of the femur is caused by what?

A

Fibrous dysplasia

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11
Q

What is fibrous dysplasia?

A

Genetic mutation resulting in lesions of fibrous tissue and immature bone

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12
Q

What is an osteoid osteoma?

A

A small nidus of immature bone surrounded by an intense sclerotic halo

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13
Q

Where are osteoid osteomas usually found?

A

Proximal femur
Diaphysis of long bones
Vertebrae

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14
Q

What are the symptoms of an osteoid osteoma?

A

Intense constant pain, worse at night due to the intense inflammatory response. This pain is greatly relieved by NSAIDs

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15
Q

What is a Brodie’s abscess?

A

Subacute osteomyelitis

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16
Q

What is a Brown’s tumour?

A

Bone lesion that arises in settings of excess osteoclast activity, such as hyperparathyroidism