MSK CATs Flashcards
Types of Disturbed fracture healing
Delayed union
- takes longer
Non-union (pseudoarthrosis)
- healing not occuring within 6-9 months
- common sites: scaphoid, femoral neck, tibial shaft
Malunion
- Healing in non-anatomical position
Refracturing
Causes of insufficiency fracture
Osteoporosis (most common)
Osteochondral injury staging system
Stage 3
- Detached but not displaced
- MRI shows high signal around the osteochondral fracture “rim sign” but not displaced
Stage 4
- fragment displaced
Stage 5
- subchondral cyst formation
mnemonic for causes of diffuse bony sclerosis is:
M: Myelofibrosis, Metastases, Lymphoma, Leukemia
S: Sickle cell disease
P: Pagets
R: Renal osteodystrophy
O: Osteopetrosis
F: Fluorosis
What is Primary myelofibrosis characterised by
extramedullary haematopoiesis
progressive splenomegaly
anaemia
variable change in the number of granulocytes and platelets including thrombocytopenia
Complications of Myelofibrosis
Gout: from hyperuricaemia due to increased haematopoietic turnover
Complications with splenomegaly
- infarction, rupture
- splenic vein thrombosis
- portal HTN
Bleeding due to thrombocytopenia
Thromboembolic event
- PE
- DVT
Stages of FICAT for AVN
Stage 2
- plain radiograph: mixed osteopenia and/or sclerosis and/or subchondral cysts, without any subchondral lucency (crescent sign: see below)
- MRI: geographic defect
- bone scan: increased uptake
Stage 3
- plain radiograph: crescent sign and eventual cortical collapse
- MRI: same as plain radiograph
Stage 4
- plain radiograph: end-stage with evidence of secondary degenerative change
- MRI: same as plain radiograph
Why femoral neck fracture prone to AVN?
Most of the femoral head blood supply is done by the extracapsular arterial ring, which is formed by the lateral femoral circumflex and the medial femoral circumflex arteries.
The femoral circumflex arteries arise from the deep femoral artery. Between them, the medial femoral circumflex artery supplies most of the blood to the head of the femur.
In cases of trauma proximal to the extracapsular arterial ring, such as femoral neck fractures, there is a considerable chance of avascular necrosis of the femoral head due to disruption of proper blood supply.
Which part of the bone is affected most by Bone Infarct and Why ?
Convex articular surfaces.
Because convex articular surfaces have smaller diameter of terminal vessels and the lack of collateral vascularisation**
Causes of Bone infarct ?
(Same causes as AVN)
- Trauma
- Sickle cell disease (rigid sickle cells leading to vaso-occlusive crises)
- vessel occlusion by nitrogen bubbles (caisson disease)
- Gaucher disease
Complications of Bone infarct ?
- MFH (most common)
- Osteogenic sarcoma
- Fibrosarcoma of bone
- Osteomyelitis
- Angiosarcoma of bone (super rare)
Nuclear medicine scan to do for bone infarct ?
Bone scan
- No uptake (photopenia) where blood supply absent
- Mildly increased uptake at periphery during acute phase
Define acute vs chronic osteomyelitis
Acute OM
- symptoms are present for <2 weeks
Chronic OM
- symptoms present for >4 weeks
Do cultures often yield positive for OM ?
No, low culture yields (only yield in ~35%). Often false-negative results
OM complications
- SCC (Marjolin ulcer)
- Osteosarcoma
- Pathological fracture
- Secondary Amyloidosis
Which of the following important features favours the diagnosis of osteomyelitis over neuropathic osteoarthropathy?
transcutaneous spread of disease — correct!
Explanation
>90% of cases of osteomyelitis spread through a transcutaneous route. Therefore, subcutaneous fat is usually involved.
Neuropathic osteoarthropathy is an aggressive form of degeneration therefore it is common to see subchondral cysts and bone erosions. It usually involves multiple joints with an articular epicenter. However, in osteomyelitis, there is a marrow epicenter.
How to diagnose early osteomyelitis in a diabetic foot with discordant bone marrow signal ?
A bone marrow to joint fluid signal intensity ratio of ≥53% on T2/STIR sequences
What is the most common location of osteomyelitis?
Lower limb
What are the 2 forms of Necrotizing fasciitis ?
Polymicrobial (Type 1)
- most common
- involves anaerob and aerobic organisms
- forms gas - due to anaerobes
Monomicrobial (Type 2)
- less common
- involves “Group A Strep” - flesh eating bacteria
- complicated by “Toxic shock syndrome”
- will not form gas, because group A strep dont form gas
Management of Necrotizing fasciitis
- Urgent surgical fasciotomy with aggressive debridement of the necrotic tissue
- Urgent empiric broad-spectrum antibiotics including anaerobic is recommended
Most common sites of septic arthritis in IV drug users ?
In intravenous drug users, the sternoclavicular and sacroiliac joints are more frequently affected.
Risk factors for septic arthritis
- Advanced age
- Bacteremia
- Sexually active
- Immunocompromised
- Rheumatoid arthritis
- Prosthetic joints
- Intraarticular injections
Ankylosing spondylitis associations
- Uveitis
- IBD
- Interstitial lung disease
- Psoriasis
- Cauda equina syndrome
DISH associations ?
- OPLL (accompanies around 50% of cervical DISH cases)
- Metabolic syndrome, obesity and diabetes mellitus
- Ossification of the stylohyoid ligament and Eagle syndrome