MSK - Back Pain Flashcards

1
Q

What are the hallmark symptoms of Cauda Equina?

A
  • Lower back pain
  • Unilateral / bilateral leg pain / weakness
  • Neurogenic bladder dysfunction - disruption to bladder sensation causes retention (bladder can’t tell brain it’s full) then overflow incontinence
  • ↓ perianal sensation - saddle anaesthesia
  • ↓ anal tone
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2
Q

What is the mechanism that causes cauda equina?

List some causes.

A

The spinal cord terminates at the conus medullaris (L1/2).

After this point spinal nerves continue as a bundle called the cauda equina. Compression of these nerves in the lumbro-sacral region causes the syndrome.

Causes:

  • Disc herniation (most common)
  • Spinal stenosis
  • Tumour
  • Trauma
  • Spinal epidural haematoma (rare anaesthetic/surgical complication)
    • Is collection of blood in space between dura and vertebrae periosteum
  • Epidural abscess
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3
Q

What are the investigations of choice for

suspected Cauda equina syndrome?

A

MRI - best evaluates neurologic compression

CT myelography - investigation of choice if can’t have MRI

Myuelography = form of fluoroscopy, inject contrast into spinal subarachnoid space

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4
Q

How is Cauda Equina syndrome treated?

A

Urgent surgical decompression within 48 hours

Discectomy or laminectomy

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5
Q

If a patient present with back pain, what conditions could cause back pain but not originate in the back?

A
  • Peptic ulcer
  • Acute pancreatitis
  • Pancreatic cancer
  • Ruptured AAA
  • Pyelonephritis - costovertebral angle pain
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6
Q

What are ‘Red Flag’ symptoms of spinal pain?

A
  • Age <20 years or >50 years
  • Fever
  • Pain at night, progressive or constant pain, pain lying flat
  • Alcohol or drug use
  • Trauma
  • Weight-loss
  • Reduced appetite
  • History of cancer
  • Neurology – weakness, numbness
  • Bladder or bowel symptoms
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7
Q

What is an osteoporotic vertebral compression fracture (wedge fracture) ?

A
  • Vertebral body fracture due to axial loading
  • Most commonly affects anterior aspect - producing wedge shaped vertebra
  • Typically are insufficiency fractures secondary to osteoporosis
  • Most common fragility frature + most common spine fracture
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8
Q

What is considered normal lumbar flexion in the modified Schober’s Test?

What is the main pathology that Schober’s test targets?

A

≥ 5cm

Ankylosing spondylitis

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9
Q

What are the initial / non-invasive treatments that come under conservative treatment of back pain / sciatica?

A
  • Education: nature of lower back pain, red flags
  • Avoid triggers
  • Weight loss
  • Local modalities: heat or ice
    • Do not offer US, PENS or TENS for management
  • Mobility devices + home modifications e.g. special chairs
  • Exercise / activity: Return to normal activities
    • Avoid bed rest for > 2 days
  • Pain management:
    • Paracetamol ineffective for back pain
    • NSAIDs = 1st line - co-prescribe PPI in pts > 45 yrs and account for GI, liver and renal toxicity
    • Weak opiods e.g. codeine
  • Physiotherapy - once pain is controlled
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10
Q

What does the natural recovery in most patients

with lower back pain look like?

A

Natural recovery is favourable - most recover from acute episode in 6-12 weeks

  • 50% recover in 2 weeks
  • 70% recover in 1 month
  • 90% recover by 4 months
  • If pt fails to recover by 4 months then they are more likely to progress to long-term chronic back pain
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11
Q

Disc herniation and spinal stenosis are 2 common casues of back pain - at what ages are each more common?

A
  • Disc herniations = more common in patients < 50 years
  • Spinal stenosis = more common in patients > 60 years
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12
Q

A prolapsed lumber disc tends to have the main features:

  • leg pain usually worse than back
  • pain often worse when sitting

A prolapsed lumbar disc produced clear dematomal leg pain + neurlogical deficits depending on the level of the prolapse.

For the following describe the pattern of leg pain + neurological deficit:

  • L3 nerve root compression
  • L4 nerve root compression
  • L5 nerve root compression
  • S1 nerve root compression
A
  • L3 nerve root compression
    • Sensory loss over anterior thigh
    • Weak quadriceps
    • Reduced knee reflex
    • Positive femoral stretch test (lie prone, knee flexed to thigh, thigh extended –> pain = +ve)
  • L4 nerve root compression
    • Sensory loss anterior aspect of knee
    • Weak quadriceps
    • Reduced knee reflex
    • Positive femoral stretch test
  • L5 nerve root compression
    • Sensory loss dorsum of foot
    • Weakness in foot and big toe dorsiflexion
    • Reflexes intact
    • Positive sciatic nerve stretch test (straight leg raise pain = +ve)
  • S1 nerve root compression
    • Sensory loss posterolateral aspect of leg and lateral aspect of foot
    • Weakness in plantar flexion of foot
    • Reduced ankle reflex
    • Positive sciatic nerve stretch test
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13
Q

For pts with lower back pain resistant to inital conservative management, what alternative non-surgical approaches can be used?

A

Pain Clinic

  • Multidisciplinary team
  • Physiotherapy
  • Occupational therapy
  • Phsychotherapy
  • Address complex issues related to pain behaviours
  • Identify psychosocial barriers to treatment
  • Different medication called ‘pain modifying medication’:
    • Gabapentin
    • Amitryptiline
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14
Q

TENS is often used by pain clinics in the treatment of resistant lower back pain.

What is TENS?

A

Transcutaneous electrical nerve stimulation

  • Small electrodes on superficial skin
  • Gate theory of pain: stimulation of large myelinated fibres at the level of the spinal cord blocks transmission of pain by small unmyelinated fibres (pain fibres) at the level of the spinal cord
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15
Q

What invasive, non-surgical interventions can be considered for back pain?

A
  • Radiofrequency denervation when:
    • Non-surgical treatments not working AND
    • Main pain source comes from structures supplied by medial branch nerve AND
    • Pain score > 5/10
    • Only use after a +ve response to diagnostic medial branch block
      • Medial branch nerve = small nerves that carry pain signals from spinal facet joints (see pic)
  • Epidural - acute / severe sciatica
    • Local anaesthetic + steorid
    • Don’t use in spinal stenosis
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16
Q

What surgical interventions can be considered in severe back pain resistant to other measures?

A

Spinal decompression

  • Discectomy
  • Laminectomy

Do not offer ‘spinal fusion’ or ‘disc replacement’

17
Q

What is Ankylosing Spondylitis?

What are the main features of ankylosing spondylitis?

A

Ankylosing spondylitis is a seronegative spondyloarthropathy

Features:

  • M > F (3:1) ~ 20-30yrs
  • Mainly affects sacro-iliac joints and axial spine
  • Inflammatory lower back pain - insidious onset, +ve response to NSAIDs
  • Lower back stiffness - lasting >30 mins, worse in morning, improves with movement/exercise
    • Long term ~20% pts develop complete spinal fusion i.e. bamboo spine
  • Iritis/anterior uveitis - ~40% of pts
  • Enthesitis - inflammation of tendons/ligaments at bony insertion (common: heel, knee, ischial tuberosities)
  • SoB - can be due to costochondral involvement causing ↓ chest expansion OR spinal kyphosis
  • ~10% of AS pts - psoriasis, IBD
  • Rare - cauda equina, apical lung fibrosis, aortic regurgitation

Examination:

  • ↓ lateral flexion
  • ↓ forward flexion - Schober’s test
  • ↓ chest expansion
  • Kyphosis
  • Loss of lumbar lordosis
18
Q

How is ankylosing spondylitis managed?

A
  • 1st line = NSAIDS e.g. Ibuprofen or naproxen
    • Adjuvent therapy = paracetamol or codeine
  • With intra-articular inflammation or enthesitis:
    • Corticosteroid injection e.g. hydrocortisone
  • With peripheral joint involvement:
    • Sulfasalazine - only good efficacy in peripheral arthritis, not axial
  • If pain is refractory to NSAIDs + other treatments:
    • TNF-alpha inhibitor e.g. etanercept (Benepali) sub-cut, adalimumab sub-cut
19
Q

Why is sulfasalazine (DMARD) only used in ankylosing spondylitis if there is peripheral joint involvement?

A

Because it doesn’t have good effiacy in managing axial arthritis

20
Q

What is spondylolysis?

A
  • Cogenital or acquired defect / stress fracture in pars interarticularis of the vertebral arch - often L4/L5
    • Pars interarticularis = part of vertebra located between inferior and superior articular processes of the facet joint (lies between lamina and pedicle)
  • Spondyolysis is the commonest cause of spondylolisthesis in children
  • Asymptomatic cases = no treatment
21
Q

What is Spondylolisthesis?

A
  • When one vertebra is displaced relative to it’s immediate inferior vertebral body
  • Features:
    • Stiff back
    • Lower back pain + shooting pain form buttocks to posterior thigh
    • Abnormal posture + gait
    • Guteal muscle atrophy due to lack of use in gait
  • If pt has radicular symptoms / signs then will often require spinal decompression + stabilisation
22
Q

What are the 5 main cancers that metastasize to bone (secondary)?

A
  1. Thyroid
  2. Lung
  3. Breast
  4. Kidney
  5. Prostate
23
Q

What surgical emergency can spinal mets cause?

A

Can cause cauda equina (via metastatic cord compression)

24
Q

What is spinal stenosis?

A

Condition in which central spinal canal is narrowed by: mass, osteophyte formation, disk prolapse etc.

Often only occurs in the elderly.

25
Q

How does spinal claudication (caused by lumbar spinal stenosis) differ from vascular claudication?

A

Spinal Claudication:

  • Pain (back/legs) worse going down hill
  • Sitting more comfortable than standing
  • Pain worse on spinal extension

Vascular claudication:

  • Pain (back/legs) worse going up hill
  • Pain worse on flexion of spine / exertion
26
Q

In pain management, patients are prescribed ‘background’ analgesia and ‘breakthrough’ analgesia for when there are flares/worsening of pain.

What fraction of background medication should breakthrough medication be?

A

1/6 th

  • ​E.g. patient’s background dose in 30g MST-continus BD (60g per day)
    • MST-continus = modified/slow-release morphine tablet
  • Breakthrough medication needs to be equal to 10mg of morphine
27
Q

How many weeks would you typically expect a muscle sprain / strain to last?

e.g. lumbar muscle sprain from lifting

A

2-4 weeks