MSK Flashcards
Describe fracture healing
Heamatoma formation - release of cytokines, growth factors, heamatoma forms, swelling, inflammation, macrophages/neutrophils remove necrotic tissue
Fibrocartilaginous callus formation (1-2 weeks) - granulation tissue forms, angiogenesis, osteoblasts begin forming spongy bone
Bony callus formation (2 months) - osteoblasts continue, fibrocartilaginous callus converted to bony (cancellous) callus, endochondral and intramembranous ossification
Bone remodelling (<7 years) - bone remodelled into compact bone, osteoclasts aid
*Wolff’s law - bone can remodel and adapt to the loads placed on it
Describe factors that affect bone healing
Patient factors - children (stem cells, thicker periosteum), smoking (nicotine/CO causes vasospasm and vasoconstriction), diabetes (defective collagen production), vitamin deficiency (vitamin D, C), corticosteroids, hyperparathyroidism (stimulates osteoclasts), hyperthyroidism (stimulates osteoclasts)
Fracture characteristics - excessive movement (disrupts repair), interposed tissues (blocking/delaying reunion), infection (osteomyelitis), large surrounding soft tissue injury (damage to blood supply, limited delivery of factors)
Describe management of hip fractures
Intracapsular displaced - THR (mobile, young, minimal comorbidities) or hemiarthroplasty
Trochanteric - sliding hip screw
Subtrochanteric - intramedullary nail
What is the Nottingham hip fracture score?
Determines risk of death/poor outcomes
Describe the Garden classification of hip fractures
Predicts Dec elopement of AVN
I - undisplaced, incomplete fracture
II - undisplaced, complete fracture
III - incompletely displaced, complete fracture
IV - completely displaced, complete fracture
Describe the Gustilo classification of open fractures
I - puncture from within to out, <1cm, minimal comminution
II - 1-10cm, moderate soft tissue damage/comminution
III - high energy trauma, farmyard/canal/sea contamination
A - adequate soft tissue damage of bone
B - extensive soft tissue loss, periosteal stripping, requires reconstructive surgery
C - vascular injury
Describe treatment of an open fracture
Initial management:
ATLS, analgesia, antiemetic, IV ABx within 3hrs, tetanus prophylaxis, control bleeding, assess soft tissue damage, neurovascular, debridememt/irrigation, photo, cover , stabilise/splint, reassess neurovascular
Surgical management:
Theatre within 24h unless vascular injury/gross contamination/compartment syndrome, aggressive debridement and irrigation, fracture stabilisation, coverage/closure
List scenarios where primary amputation is necessary
Uncontrollable haemorrhage Incomplete traumatic amputation 4-6 hours ischaemia Segmental muscle loss of two compartments Bone loss > 1/3 tibia
List signs and treatment of acute compartment syndrome
Pain (+ on passive stretch) Swollen tense compartment Paraesthesia Pressure >40mmHg --> dermatofasciotomy
What is the most common primary bone neoplasia?
Myeloma (40%)
Describe types of changes on X-ray in keeping with neoplasia
Lyric
Sclerotic
Mixed
What cancers cause lytic bone changes?
Renal Thyroid Adrenal Uterine GI
What cancers cause sclerotic bone changes?
Prostate
Breast
Renal (TCC)
What cancers cause mixed sclerotic/lytic bone changes?
Primary bone tumour (Ewing’s sarcoma/osteosarcoma/chondrosarcoma)
Which cancers metastasise to bone?
Thyroid Breast Lung Renal Prostate
List red flag symptoms of back pain
Age <16 or >50 new onset
Non mechanical
Thoracic
Malignancy history, unexplained weight loss
Long term steroid use
Fevers/rigors, recent significant infection
Difficulty passing urine (retention), urine/faecal incontinence, bilateral sciatica, saddle anaesthesia, decreased anal tone
List yellow flag symptoms of back pain
Attitudes Beliefs Compensation Diagnosis Emotions Family Work
Describe the conditions cauda equina syndrome, myelopathy, radiculopathy
Cauda equina - pressure on nerve roots at cauda equina of spinal cord due to prolapsed disc/infection/cancer/lumbar spinal stenosis
Myelopathy - injury to spinal cord due to severe compression
Radiculopathy - pinched nerve
Describe how you would undertake an examination of the spine
Look - posture, asymmetry, scoliosis, muscle wasting, soft tissue abnormalities, cafe au lait spots, cervical lordosis/thoracic kyphosis/lumbar lordosis
Feel - temperature, spinous processes, sacroiliac joints, paraspinal muscles
Move - lateral flexion, lumbar flexion and extension cervical spine flexion and extension/rotation/deviation, thoracic rotation
Special tests - modified shobers test, femoral nerve stretch test, straight leg raise
Describe the shoulder joints and how it is stabilised
Ball and socket joint
Joints - sternoclavicular, acromioclavicular, glenohumeral, scapulothoracic
Stabilised by - rotator cuff muscles, labrum, glenohumeral ligaments