MSK Flashcards
Vitamin D values
< 30 = Deficient – high dose replacement
30 – 50 = Insufficient – medium dose
> 50 = Sufficient - none
What does vitamin d do?
- Helps regulate amount of calcium and phosphate in the body.
- These in turn required to keep bones, teeth and muscles healthy.
- Check levels in suspected fragility fractures
Indications for DEXA scan
- High fragility fracture risk score (Frax or Qfracture)
- Over 50 yrs with history of fragility fractures
- Under 40 with major risk factor for fragility fracture + refer to FLS
Diagnosis of osteoporosis using DEXA scan- value
T score of -2.5 or below is a diagnosis of osteoporosis
Indications for Vitamin D levels
osteomalacia (or rickets)
fargility fractures
Can you differentiate between osteomalacia and osteoporosis using DEXA
No
What is osteomalacia?
metabolic bone disease characterised by incomplete mineralisation of the underlying mature organic bone matrix
inadequate levels of calcium, phosphate or vitamin D,
What is arthroscopy?
Surgical procedure where thin telescope with light source (arthroscope) to look inside joints.
Diagnostic or Arthroscopic surgery.
Mainly used to investigate or treat knee problems.
Can be used in other joints too.
Indications for joint aspiration
any patients with inflamed joints with no established diagnosis.
Joint aspiration of gout vs septic arthritis:
Gout: needle shaped negatively-birefringent uric acid crystals
Septic arthritis:
1. joint fluid aspiration appears cloudy or purulent
- cell count with WBC > 50,000 is considered diagnostic for septic arthritis
- gram stains only identifies infective organism 1/3 of time
Rheumatoid + osteoarthritis inflammatory differences
High ESR + CRP = RA
Normal ESR + CRP = Osteroarthritis
When to refer urgently for rheumatoid arthritis?
- Small joints of the hands or feet are affected
- More than one joint is affected
- There has been a delay of 3 months or longer between the onset of
symptoms and the person seeking medical advice - Do not delay referral if blood tests are normal or results have not returned from the laboratory.
- Early intervention may help prevent irreversible joint damage
Ix for SLE
- Anti-dsDNA
- Anti-smith
antibodies - ANA +
–> confirmatory of SLE with symptoms
Anti-CCP specific to…
Rheumatoid arthritis
Rheumatoid factor
Non- specific marker