MS Flashcards
1
Q
Clinical Features of MS
A
Pyramidal dysfunction Optic neuritis Sensory symptoms (Dorsal column loss) Lower urinary tract dysfunction Cerebellar dysfunction Fatigue
2
Q
Clinical course of MS
A
Relapsing remitting
Secondary progressive
Progressive relapsing
Primary progressive
3
Q
Treatment of fatigue
A
Amantadine
Modafanil (if sleepy)
4
Q
DMT - First line
A
Interferon - Avonex, Rebif, Betaseron
Tecfedira - first line in RR MS
5
Q
DMT - Second line
A
Monoclonal Antibody
- Fingolimod
6
Q
DMT - Third line
A
Mitoxantrone (Relapsing progressive MS)
7
Q
Tysabri
A
Used in highly active RR MS.
high disease activity despite treatment with an interferon
8
Q
Baclofen
A
GABA derived drug
Antispasmodic
9
Q
Oxybutinin
A
Anticholinergic
Used in detrusor instability and urinary incontinence in MS.
10
Q
Propranolol
A
Beta blocker to help with tremor
