MS

Question 1

What patient population does MS affect the most?

Answer 1

Females

Question 2

What is the most common type of MS?

Answer 2

Relapsing-remitting

Question 3

What are the 4 types of MS?

Answer 3

1. Clinically isolated syndrome
2. Relapsing-remitting
3. Secondary-progressive
4. Primary-progressive

Question 4

What is the initial treatment for MS?

Answer 4

Interferons

Question 5

What are the 5 interferons?

Answer 5

1. Avonex
2. Betaseron
3. Extavia
4. Rebif
5. Plegridy

Question 6

What are the main ADRs for interferons?

Answer 6

1. Flu-like symptoms
2. Depression

Question 7

What is a side effect of copaxone that only happens once?

Answer 7

Flushing, palpitations, chest pain, SOB, anxiety (looks like a CV event)

Question 8

What is an SE of copaxone that effects the skin?

Answer 8

Skin may appear “sunken in” overtime due to loss of subcutaneous fat

Question 9

What are the 2 main ADE of gilenya?

Answer 9

1. Headache
2. Flu like symptoms

Question 10

What is a serious ADE of gilenya?

Answer 10

Bradycardia

Question 11

What patients is gilenya contraindicated?

Answer 11

Patients with a previous 6 month history of CV events

Question 12

What can gilenya cause?

Answer 12

Fetal harm

Question 13

Why does mayzent need titrated?

Answer 13

Cardiac ADE

Question 14

What are the 2 ADRs of aubagio?

Answer 14

1. Hair loss, thinning
2. Diarrhea

Question 15

What are the 3 serious adverse effects of Aubagio?

Answer 15

1. Hepatotoxicity
2. Bone marrow effects/infections
3. Peripheral neuropathy

Question 16

What drug cannot be used in pregnancy?

Answer 16

Aubagio

Question 17

What drug is approved for relapsing forms of MS?

Answer 17

Ponvory

Question 18

What are the 4 common adverse effects of tecfidera?

Answer 18

1. Flushing
2. Abdominal pain
3. Diarrhea
4. Nausea

Question 19

What’s a serious ADR of tecfidera?

Answer 19

Lymphopenia

Question 20

What are the 2 drugs that are similar to tecfidera?

Answer 20

1. Vumerity
2. Bafiertam

Question 21

What drug, similar to tecfidera, has less GI effects than tecfidera?

Answer 21

Vumerity

Question 22

What is a SE seen with tysabri?

Answer 22

Infusion reactions

Question 23

What is a serious ADR of tysabri?

Answer 23

Progressive multifocal leukoencephalopathy

Question 24

What do you test for for a patient treated with tysabri?

Answer 24

JCV virus

Question 25

How many doses in total do patients receive when taking lemtrada?

Answer 25

8 days total

Question 26

What’s a common ADE for lemtrada?

Answer 26

Thyroid gland dysfunction

Question 27

What are 3 serious ADRs of lemtrada?

Answer 27

1. Autoimmunity
2. Infusion reactions
3. Malignancies

Question 28

What is a common ADE that’s seen with novantrone?

Answer 28

Bluish discoloration of the sclera and urine

Question 29

What’s the BBW for noavantrone?

Answer 29

1. Extravasation
2. Heart failure
3. Neutropenia
4. Secondary malignancy

Question 30

What is the first and only investigational medicine to significantly reduce the progression of physical disability in primary progressive MS?

Answer 30

Ocrevus

Question 31

What is the only self injected treatment for MS?

Answer 31

Kesimpta

Question 32

What drug is specialty only and has limited distribution?

Answer 32

Ampyra

Question 33

What medication is adjunct therapy in MS?

Answer 33

Ampyra

Question 34

When should patients take Ampyra?

Answer 34

Every 12 hours

Question 35

What is the use of Ampyra contraindicated in?

Answer 35

Patients with a history of seizures

Question 36

How is Ampyra eliminated?

Answer 36

Renally excreted