MRCS Drugs Flashcards

1
Q

How do thiazide diuretics work?

A

Inhibit sodium channel of DCT

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2
Q

Which diuretics inhibit Na channel of DCT?

A

Thiazides

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3
Q

How do loop diuretics work? Be specific

A

Inhibit Na/K/Cl symporter of thick ascending loop of henle by competing for Cl binding site

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4
Q

How is metoclopramide drug effect mediated?

A

Via vagus nerve

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5
Q

What drug increases rate of gastric emptying in vagotomised stomach? What does not?

A

Erythromycin does via motilin receptor

Metoclopramide needs vagus nerve so does not

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