MRCS Drugs Flashcards
1
Q
How do thiazide diuretics work?
A
Inhibit sodium channel of DCT
2
Q
Which diuretics inhibit Na channel of DCT?
A
Thiazides
3
Q
How do loop diuretics work? Be specific
A
Inhibit Na/K/Cl symporter of thick ascending loop of henle by competing for Cl binding site
4
Q
How is metoclopramide drug effect mediated?
A
Via vagus nerve
5
Q
What drug increases rate of gastric emptying in vagotomised stomach? What does not?
A
Erythromycin does via motilin receptor
Metoclopramide needs vagus nerve so does not