MRCP CANNOT REMEmber -PART 1 Flashcards
side effects of lithium toxicity other than nephrotoxic and tremor ?
hyperparathyroiidism - leading to increased calcium
idiopathic intracranial hypertension
hypothyroidism
weight gain
lithium blood levels normally checked every ?
3 months
what contributes to lithium toxicity ? (OTHER THAN ACE AND ARB AND DEHYDRATION )
NSAID and metronidazole
features of bells palsy ?
FORHEAD IS AFFECTED
post auricular pain, dry eyes , hyperacusis
Mx of bells palsy ?
ALL PATINET’S SHOULD RECIEVE PREDNISLONE WITHIN 72 HOURS
if sever facial palsy then can add anti virals
ARTFICAL TEARS AND LUBRICANT TO PREVENT EXPOSURE KERATOPATHY
if no improvement in paralysis - ENT REFERRAL
bells palsy more common in ?
pregnant women
NOONAN SYNDROME defect in ?
chromosome 12 - AFFECTS MALES - AD
features of noonan syndrome
pulmonary valve stenosis
factor XI deficiency
ptosis
low set ears
triangular shaped face
myoclonic dystrophy features ?
AD
dysarthria
diabetes
distal TONIC muscle weakness
dysphagia
FRONTAL BALDING
PTOSIS
long haggard face
cataracts
cardiomyopathy - HEART BLOCK FIRST DEGREE
MILD MENTAL IMPAREMENT
S3 gallop heart sound heard in other than heart failure ?
constrictive pericarditis
and mitral regurgitation
thiazides affect which part of the distal convoluted tubule ?
proximal part of the DCT - in the sodium chloride channels
WHAT IS THE MANAGMNET OF cryptospordosis ?
NITAZOXANIDE - if immunodeficient such as HIV
features of pseudohypoparthyroidism ?
short 4th and 5th metacarpals
obesity
round face
learning difficulties
short stature
MX of pseudohypoparthyroidism ?
INFUSION OF PTH
other than atovaquone +proguanil (madrone) for the prophylaxis of malaria what other drugs are used ?
chloroquine
doxycycline
mefloquine
features of discoid lupus erythematous ?
follicular keratin plugs
raised rash - sometimes scaly
photosensitive to sunlight
lesion heal with ATROPHY SCARING AND PIGMENTATION
MX od discoid lupus erythematous ?
TOPICAL PREDNSILONE
OR HYDROXYCLOROQUINE
investigative features of antiphosoplipid syndrome ?
THROMBOCYTOPENIA
and PROLONGED APTT
prophylaxis of antipholipid syndrome ?
primary prophylaxis - events not occurred
aspirin
event occurred - secondary prophylaxis
INR TARGET 2-3
warfarin life long
if reoccurring
increasie INR target to 3-4
LIFE LONG WARFARIN
AND CONSIDER ADDING ASPIRIN
if pregnant - low dose aspirin and LMWH
adverse effects of ciprofloxacin ?
prolong QT
lower seizure threshold
and tendinopathy
what are poor prognostic features of sarcoidosis other than absence of erythema nodosmun ?
black and african
insidious onset
symptoms more than 6 months
extrapulmonary - lupus pernio and splenomegaly
stage 3 and 4
features of whipple disease ?
lymphadenopathy
hyperpigmentation
pleurisy / pericarditis
ophthalmoplegia
what are the features of neurofibromatosis other then axillary and groin freckles ?
peripheral neurofibromas
IRISH HAMARTOMAS - litchi nodules
pheochromocytoma
WHAT ARETHE FEATURES OF VON HIPPER LINDAU SYDROME - OTHER THAN CLEAR CELL CARCINOMA
ENDOLYMPHATIC SAC TUMORS
PHEOCHROMOCYTOMA
RENAL CYST
RETINAL HEMANGIOMA - WHICH CAN BE VITROUS HEMORRHAGES
CEREBELLAR HEMANGIOMA
features of Tuberous sclerosis ?
RETINAL HAMARTOMAS
RHABDOMYOMA
POLYCSTIC KIDNEYS
RENAL ANGIOMYLIPOTOMA
managmnet of Gillian bare syndrome ?
IVIG
managmnet of myasthenia gravid ?
LONG ACTING ACETYLCHOLINESTRASE inhibtors - pyridostigmine
then prednisolone
azathioprine or ciclosporin
exacerbating factors of myasthenia gravid other than beta blockers ?
penicillin
quinine
procainamide
phenytoin
gentamcin
exacerbating factors of psoriasis ?other than beta blockers
alcohol
lithium
NSAIDS
ace
drug inducing lupus ?
procainamide
hydralazine
Less common causes
isoniazid
phenytoin
causes of erythema nodosum ? OTHER THAN TB / SARCOIDOSIS / PREGNANCY / INFLAMMATORY BWEL DISEASE
LYMPHOMA
BECHET DISEASE
STREPTOCOCCI
PENIILLIN
BRUCELLOSIS
SULPHONAMIDES
COCP
