MP323 - STROKE/TIA Flashcards

1
Q

stroke

A

clinical syndrome characterised by sudden onset of rapidly developing focal or global neurological disturbance which lasts more than 24 hours or leads to death

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2
Q

transient ischaemic attack (TIA)

A

transient (less than 24 hours) neurological dysfunction caused by focal brain, spinal cord, or retinal ischaemia, without evidence of acute infarction

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3
Q

2 types of stroke

A

ischaemic
haemorrhagic (less common)

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4
Q

thrombotic stroke

A

ischaemic stroke
blood clot (thrombus) blocks flow of blood in brain

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5
Q

embolic stroke

A

ischaemic stroke
fatty plaque or blood clot (embolism) breaks away and flows to brain where it blocks an artery

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6
Q

cerebral haemorrhage

A

haemorrhagic stroke
break in blood vessel (aneurysm) in brain

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7
Q

small vessel (lacunar) ischaemic stroke

A

small vessel deep in the brain affected

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8
Q

large vessel (thrombotic) ischaemic stroke

A

hyperlipidaemia with unstable plaque

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9
Q

cardiogenic (embolic) ischaemic stroke

A

clot moves from the heart and lodges in a vessel in the brain

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10
Q

initial potential complications of stroke

A

haemorrhagic transformation
cerebral oedema
seizures
venous thromboembolism
cardiac complications
infection

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11
Q

long-term complications -> mobility problems

A
  • hemiparesis or hemiplagia
  • ataxia
  • falls
  • spasticity and contractures
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12
Q

long-term complications -> sensory problems

A

loss or alteration in sensations such as touch, temperature and pain

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13
Q

long-term complications -> continence problems

A
  • urinary and faecal problems are common and can persist long-term
  • urinary incontinence can increase the risk of skin breakdown and can be exacerbated by constipation
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14
Q

long-term complications -> pain

A

due to neuronal damage

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15
Q

long-term complications -> dysphagia

A
  • difficulty in swallowing foods, fluids and saliva
  • associated with aspiration pneumonia, disability and death
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16
Q

acute stroke care when admitted

A
  • admit to stroke unit
  • imagining (CT)
  • swallow test (nil by mouth)
  • assess medicines
17
Q

thrombolysis - alteplase

A

tissue plasminogen activator
licensed within 4.5 hours of the onset of symptoms

18
Q

alteplase dose and administration

A

0.9mg/kg (max dose 90mg)
10% as bolus over 2-3min
90% as infusion over 60min

19
Q

complications of thrombolysis

A

intra-cerebral haemorrhage
angioedema
minor bleeding is common (IV site)
anaphylaxis