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Neuro Shelf > Movement Disorders > Flashcards

Movement Disorders Flashcards

1
Q

Rate-limiting step in DA production?

A

Tyrosine Hydroxylase

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2
Q

Converts L-dopa to DA?

A

Dopa decarboxylase

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3
Q

Sinemet = ?

A

C + L Dopa

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4
Q

Bromocriptine?

A

DA agonist

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5
Q

Pergolide?

A

DA agonist

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6
Q

Pramipexole?

A

DA agonist

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7
Q

Ropinirole?

A

DA agonist

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8
Q

Amantadine MOA?

A

Stimulates DA neurons to release DA

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9
Q

Tolcapone/Entacapone MOA?

A

COMT inhibitors

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10
Q

Benzotropine use and MOA?

A

Anti-cholinergic for Parkinsons

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11
Q

Action Tremor localization?

A

Cerebellum

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12
Q

What can resolve essesential tremor?

Pharm vs non-pharm?

A

Alcohol

B-blocker
Klonopin

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13
Q

Other action tremor causes?

A 
Lithium
Valproate
Amiodarone
B-agonist
Caffiene
Alcohol withdrawal
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14
Q

MRI purpose in Parkinsons?

A

Rule out treatable cause

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15
Q

Tx. for Parkinsonss Drug induced dyskinesia?

A

Amantadine

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16
Q

Multiple Systems atrophy symptoms?

A

PD
Ataxia
CS
Autonomics

17
Q

MSA cause?

A

a-synuclein defect

18
Q

Parkinsons vs. LBD vs. MSA?

A 
PD = Striatum
LBD = Striatum and cortex
MSA = Striatum, autonomics, cerebellum
19
Q

Athetosis?

A

Slow distal writhing

20
Q

Primary Distonia in Ashkenazi Jews?

A

Age

21
Q

Primary distonia in pt

A

Dopa responsive dystonia

22
Q

Symptomatic TX for dystonia?

A

Baclofen, anti-ACh, botox

23
Q

Tx for Tourettes?

A 
A2 agonist (Clonidine)
Anti-psych (Risperidone)
24
Q

Tremor disappears during sleep indicates?

A

Basal Ganglia origin
PD
HD
Wilsons

25
Q

Work-up for tremor?

A 
Hx of trauma?
Other signs? -- stroke
TSH
Ceruloplasmin
Heavy metals

Neuro Shelf (9 decks)

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