Movement Disorder Drugs Flashcards by Zak Reneau | Brainscape

Q

What is the MOA and disease treated of Levodopa?

A

D2 agonist, PD

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Q

What is the MOA and disease treated of Bromocriptine?

A

D2 agonist, PD

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Q

What is the MOA and disease treated of Ropinirole?

A

D2 agonist, PD

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Q

What is the MOA and disease treated of Pramipexole?

A

D3 agonist, PD

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Q

What is the MOA and disease treated of Carbidopa?

A

DOPA decarboxylase inhibitor, PD

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Q

What are the D2 agonist drugs?

A

Levodopa, Bromocriptine, Ropinirole

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Q

What is the MOA and disease treated of Rasagiline?

A

MAO-B inhibitor, early PD

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Q

What is the MOA and disease treated of Selegiline?

A

MAO-B inhibitor, early PD

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Q

How are Rasagiline and Selegiline different?

A

Rasagiline is more potent

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Q

What is the MOA and disease treated of Entacepone?

A

COMT inhibitor, PD to increase Levodopa

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Q

What is the MOA and disease treated of Tolcapone?

A

COMT inhibitor, PD to increase Levodopa

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Q

What is the MOA and disease treated of Benztropine?

A

Anticholinergic, PD tremors and rigidity

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Q

What is the MOA and disease treated of Biperiden?

A

Anticholinergic, PD tremors and rigidity

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Q

What is the MOA and disease treated of Orphenadrine?

A

Anticholinergic, PD tremors and rigidity

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Q

What is the MOA and disease treated of Procyclidine?

A

Anticholinergic, PD tremors and rigidity

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Q

What is the MOA and disease treated of Trihexyphenidyl?

A

Anticholinergic, PD tremors and rigidity

Q

What are the Anticholinergic drugs used to treat PD?

A

Benztropine, Biperiden, Orphenadrine, Procyclidine, Trihexyphenidyl

Q

What is the MOA and disease treated of Reserpine?

A

Inhibits monoamine transporter causing increased DOPA release, HD

Q

What is the MOA and disease treated of Tetrabenazine

A

Inhibits monoamine transporter causing increased DOPA release, HD

Q

Which drugs are used to treat HD?

A

Reserpine, Tetrabenazine

Q

What is the MOA and disease treated of Riluzole?

A

Inhibits Glutamate release causing inhibition of NMDA receptors, ALS

Q

Which drug is used to treat ALS?

A

Riluzole

Q

What is the MOA and disease treated of Penicillamine?

A

Copper chelator, Wilsons

Q

What is the MOA and disease treated of Trientine?

A

Copper chelator, Wilsons

Q

What is the MOA and disease treated of Potassium Disulfide?

A

Inhibits GI absorption of Copper, Wilsons

Q

What is the MOA and disease treated of Zince Acetate?

A

Inhibits GI absorption of Copper, Wilsons

Q

What is the MOA and disease treated of Zinc Sulfate?

A

Inhibits GI absorption of Copper, Wilsons

Q

What are the drugs that treat Wilsons disease?

A

Penicillamine, Trientine, Potassium disulfide, Zinc acetate, Zinc sulfate