Mousallem Thrombocytopenia

Question 1

the characteristic finding of thrombocytopenia rather than hemophilia

Answer 1

petechiae are the characteristic finding in thrombocytopenia where as pts with coagulation disorders like hemophilia tend not to have petechiae but rather deep bleed into tissue *muscle** and joints or to have delayed bleed

Question 2

What are symps accompanied with malignancy or AI disorder causing thrombocytopenia

Answer 2

Systemic symptoms:
Fever
Wt loss
Bone pain
Appetite change

Question 3

HUS symptoms:

Answer 3

-prodromal illness: abd pain and diahria
- AKI
Thrombocytopenia
Hemolytic anemia

Question 4

Wiskot aldrich syndrome

Answer 4

-X linked hereditary disorder
-fam hx of microthrombocytopenia affecting male
-severe eczema
-increased risk of ID and (malignancy) leukemia

Question 5

Nutritional deficiency due to mal absorption or very restricted diet predispose to thrombocytopenia

Answer 5

T
Iron- vit B12 - folate

Question 6

Thrombocytopenia associated with
Systemic symptoms
Lymphadenopathy
Hepatospleno megally
Suggests typical diagnosis

Answer 6

F
Atypical dg: malignancy or proliferative dz

Question 7

What do we in peripheral smear of
ALL

Answer 7

Lymphocytes, anemia, thrombocytopenia

Question 8

What do we in peripheral smear of
Microangiopathic hemolytic anemia

Answer 8

-schizocytes
-spherocytes
-fragmeneted cells
-thrombocytopenia
-anemia

Question 9

What do we in peripheral smear of
Hereditary macrothrombocytopenia

Answer 9

Giant platlets