Motor Neurone Disease Flashcards
1
Q
What are the key features of MND?
A
- UMN and LMN signs without sensory problems
- Muscle weakness with potentially problems with speech, swallow and breathing
2
Q
What are the common sites of onset of MND?
A
- Extremities 70%
- Bulbar 25%
- Thoracic 2%
3
Q
What are therapeutic interventions for the thoracic variant of MND?
A
- Early non-invasive intubation with compensation
4
Q
What must you be suspicious of should a patient present with MND type motor symptoms which were preceded by behavioural abnormalities?
A
Frontotemporal dementia
5
Q
What are clinical signs of UMN problems?
A
- Spasticity
- Hyperreflexia
- Babinski sign (extensor plantar reflexes)
- Moderate weakness
- Psuedobulbar affect (uncontrollable emotional displays)
6
Q
What are clinical signs of LMN problems?
A
- Severe weakness
- Fasciculations
- Muscle cramps
- Hyporeflexia
- Muscle hypotonicity and atrophy
