motor deficits

Question 1

initial symptoms in MS

Answer 1

• motor sensory optic SEPARATED in TIME and SPACE
• TINGLING and NUMBNESS most common initial
• optic neurtitis
• acute focal motor weakness
• balanche difficulties

Question 2

how to tx MS acute attack

Answer 2

steroids

Question 3

Chronic MS drugs

Answer 3

B interferons, linoleic acid, and glatirmer acetate

Question 4

rapidly evolving, symmetric, polyradicular with motor > sensory

Answer 4

GBS (AIDP) acute inflammatory demyelinating plyneuropathy

Question 5

GBS sx required for diagnosis

Answer 5

• progressive weakness in arms and legs

- areflexia

Question 6

symptoms absent in ALS

Answer 6

Pain, sensory symptoms, incontinence, eye

Question 7

Amytophic Lateral Sclerosis is a disease of what?

Answer 7

degeneration of upper and lower motor neurons

Question 8

How do ALS pts. usually present? other sx?

Answer 8

• most present w weakness in arms or legs, usually assymetric
• 15% w facial weakness
• fasiculations
• stiffness
• weight loss, atrophy
• fatigue

Question 9

Upper motor neuron symptoms regarding
weakness
atrophy
fasiculations
reflexes
tone

Answer 9

Upper motor neuron symptoms regarding

weakness: yes
atrophy: not initially
fasiculations: no
reflexes: hyper-reflexive (loss inhib tone)
tone: increased (loss inhib tone)

Question 10

Lower motor neuron symptoms regarding
weakness
atrophy
fasiculations
reflexes
tone

Answer 10

Lower motor neuron symptoms

weakness: yes
atrophy: yes
fasiculations: yes
reflexes: decreased
tone: decreased

Question 11

Treatment of ALS and prognosis

Answer 11

Riluzole extends time till vent. 3-5 year survival after diagnosis wo vent.

Question 12

muscle fatigue with repetition of muscle movement is

Answer 12

myasthenia gravis

Question 13

treatment options and prognosis of MG?

Answer 13

mestinon (ACHi); immunosupressive; prednisone; thyectomy; plasmaphorsesis; IViG