Motion Sickness

Question 1

What receptors are in the chemoreceptor trigger zone?

Answer 1

DA
5-HT
Ach

Question 2

What is vertigo usually caused by?

Answer 2

Inner ear condition

Question 3

What are the treatments of vertigo

Answer 3

Antihistamines (meclizine, dimenhydrinate)
Benzodiazepines

**both suppress the vestibular (inner ear)

Question 4

What is the treatment of motion sickness?

Answer 4

Antihistamines and Anticholingerics

Anticholinergic:
-Scopolamine (Transderm)

Antihistamines:
-diphenhydramine (Benadryl)
-dimenhydrinate (Dramamine)
-meclizine (Dramamin all day less drowsy)

Question 5

What is the dosing schedule of Scopolamine (Transderm) for motion sickness?

Answer 5

apply 1 patch BEHIND the ear at least 4 hours before effect is needed

*may use new patch every 3 days PRN

Question 6

What are some counseling points for Scopolamine (Transderm)?

Answer 6

AVOID alcohol!!!
SE: dry mouth, drowsiness, dizziness, confusion, pupil dilation

**ANTICHOLINERGIC

Remove patch before an MRI

do NOT use in children
do NOT drive

Question 7

Dramamine SE

Answer 7

Dimenhydrinate
Warning: CNS depression, increased IOP

SE: dizziness, drowsiness, dry mouth