most important exam questio answers imo Flashcards
difference between the structure of globular and fibrous proteins and link that to haemaglobin and collagen (1)
globular proteins are compact and spherical (1) tehy have hydrophillic R groups on the otuside (1) therefore they are soluble in water (1 ). EXAMPLE of a globular protein ins INSULIN (1 )
functuions of haemaglobin : carries and transports oxygen carbon dioxide (1)
contains fe 2+ prosthetic group (1)
.polypeptide chains within haemagblobin have tertiary structure (1)
collagens : long, fibrous (1) and fibres form H bonds with adjacent chains (1) and they are insoluble (1) so they have few hydrophillic group (1) . they are also strong and provide strength (1)
Collagen: high proportions of glycine so chains lie closer together (1) and collagen forms crosslinks between molecules (1) which are STAGGERED to avoid weakpoints (1) . they also form part of the cartillage (1)
describe how the structure of antibodies allows them to perform their function ? (7 )
2 light chains and 2 heavy chains / 4 polypeptide
chains ;
variable region allows , binding / attachment , to
antigen ;
two variable regions allow binding of more than
one (of the same) antigen ;
variable region on different antibodies allows specificity
to different antigens ;
constant region allows , recognition by / attachment to /
binding to , (named) phagocytes ;
hinge (region) allows flexibility ;
disulfide , bonds / bridges , hold , polypeptides / light
and heavy chains , together ;
REMEMBER: they for ANTIGEN ANTIBODY COMPLEX1
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