important processes (MEMORISE ) Flashcards
phagocytosis
1) phagocyte is attracted by chemicals produced by the pathogen 2) phagocyte recognises pathogen as non-self and binds to it 3) phagocyte engulfs the pathogen to form phagosome - lysosome moves towards phagosome and combines with it forming a phagolysosome 4) In phagolysosome, enzymes break down the pathogen 5) Digested pathogen absorbed by phagocyte - antigens combine with MHC in the cytoplasm 6) MHC is displayed on phagocyte membrane, making an antigen presenting cell (APC)
antibodies
Y shaped glycoproteins
saprotroph
obtain nutrition from dead organic matter
what happens in the response to cell-mediated immunity
1) APC presents the antigen on the surface of the cell 2) T helper cells have receptors which complement the antigen 3) when the t helper cell binds to the antigen, the t helper cell becomes activated (clonal selection) 4) They produce interleukins 5) this stimulates more T cells that are specific to the antigen to divide and form clones (clonal expansion) 6) the clones then do one of four things: - produce interleukins to stimulate phagocytosis -produce interleukins to stimulate B cells to divide - differentiate into T killer cells - differentiate into T memory cells
how does the body respond to humoral immunity?
1) B lymphocytes covered in antibodies bind to specific antigens (clonal selection) OR B lymphocytes engulfs the pathogen and present the antigen on the surface 2) With the help from the T helper cell interleukins, the B cells are activated and divide by clonal expansion 3) the clones develop into either plasma cells producing antibodies or into memory cells
the process of blood clotting
When you cut yourself: -Platelets come in contact with collagen in the skin -Platelets stick to each other -Secrete several substance Thromboplastin – enzyme that leads to the formation of a blood clot Serotonin – causes smooth muscle in walls to contract (narrowing reduces blood supply to area -Clot dries out, forming a hard, tough scab -Epidermal cells below start to grow, sealing wound permanently -Damages blood vessels regrow -Collagen fibres deposited to give new tissue strength