Mosby 17 Flashcards

1
Q

Elderly Diseases: Urinary incontinence - stress

Symptoms

Associated disease

Postovoid residual

A

Small volume incontinence with sneezing, laughing, coughing, etc.

Can have ass’d pelvic organ prolapse

Normal postvoid residual

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2
Q

Elderly Diseases: Urinary incontinence - urge

Description

Associatied

Postvoid

A

Uncontrolled urge to void

“I get the sudden urge to pee so quickly I can’t make it to the bathroom”

Can be related to CNS disorder

Normal postvoid residual

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3
Q

Elderly Diseases: Urinary incontinence - Overflow

Symptoms

Associated symptoms

Postvoid

A

Small volume incontinence 2/2 uring leaking around an obstructionBPH: pressure builds in bladder until it is slowly squeezed through the narrowed urethra

Sx: dribbling, nocturia, incomplete emptying

Neurogenic bladder: Bladder can’t contract well, so pressure builds in the bladder until it starts to leak out

High postvoid residual

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4
Q

Elderly Diseases: Urinary incontinence - Functional

Symptoms

Postvoid volume

A

In pt with a disability that prevents them from getting to the bathroom in time or prevents them from knowing they need to pee (E.g. severe dementia)

They would be able to make it to the bathroom if they didn’t have the disability

Normal postvoid residual

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5
Q

Elderly Diseases: Fecal incontinence

Three causes

A

Three major causes

Fecal impaction- “overflow incontinence”; diarrhea moves around the hard stool

Underlying disease

Neurogenic disorders

Stroke, dementia, degeneration of nerves to the area leading to loss of sphincter tone

PE: Can see decreased sphincter tone on DRE

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6
Q

Peds Diseases: Intussusception

What is it?

Population and ass

Presentation

Physical

Diagnosis

A

Prolapse of one part in intestine into another leading to obstruction

Common cause of obstruction in kids

Most commonly 2/2 lymph node hyperplasia or Meckel diverticulum

In adults, most commonly 2/2 cancer

Classic sx: Colicky abdominal pain (kid doubled over in pain) with “red currant jelly” stools

PE: sausage shaped mass in R or LUQ

Dx AND Tx: air contrast enema

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7
Q

Peds Diseases: Pyloric Stenosis

Symptoms

Association

Physical exam

A

Hypertrophy of pylorus

Sx: projectile vomiting in a few week old infant with failure to thrive

Ass’d with erythromycin use and more common in first born males

PE: Olive shaped RUQ mass

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8
Q

Peds Diseases: Meconium Ileus

What is it

Symptoms

Diagnosis

Other possible diagnosis

A

Distal intestinal obstruction due to thick inspissated meconium “clogging” up the system

Failure to pass meconium within first 24 hours

Most commonly in cystic fibrosis

Sx: obstructive sx (vomiting, abdominal distention)

Major differential diagnosis includes Hirschprungs disease

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9
Q

Peds Diseases: Biliary Atresia

What is it

Symptoms

Diagnosis

Treatment

A

Congenital obstruction or absence of bile ducts leading to bile flow obstruction

Can occur postnatally (thought to be infectious) or embryonic

Sx of cholestasis (jaundice, clay colored stools, dark urine) in first few weeks of life

Dx: US

Tx: Most often requires liver transplant (esp. if internal ducts are affected)

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10
Q

Peds Diseases: Meckel Diverticulum

What is it

Rule of 2

Cause

Symptoms

What can cause

A

Outpouching of ileum

Rule of 2’s: 2 in. long, withing 2 feet from terminal ileum, presents by 2 years of age, in 2% of population

2/2 incomplete obliteration of the vitelline duct

Sx: painless rectal bleeding

Can cause intussusception

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11
Q

Peds Diseases: Necrotizing enterocolitis

Decscription

Symptoms

X-Ray

A

Intestinal necrosis occurring in premature infants

Sx: failure to thrive, vomiting, bloody stools, peritoneal signs, very sick premie

AXR: pneumatosis intestinalis (air in bowel wall)

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12
Q

Peds Diseases: Neuroblastoma

What is it

Symptoms

Comparison to wilms tumor

A

Malignancy of peripheral sympathetic nervous system

Most commonly in adrenal medulla

Sx: most commonly asymptomatic abdominal mass, but can cause different mass-related local symptoms based on location

Crosses midline (vs. Wilms tumor)

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13
Q

Peds Diseases: Wilms Tumor

What is it

Population

Syndrome

Symptoms

A

Most common intraabdominal tumor in kids

In 2-3 year olds

Mostly sporadic, but can be familial

WAGR syndrome: Wilms tumor, aniridia, GU abnormalities, mental retardation

Sx: Painless abdominal mass (typically doesn’t cross midline), may have hematuria

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14
Q

Peds Diseases: Hirschprung Disease

What is it

Presnetation in older kids

Sign

A

Lack of parasympathetic ganglion cells in distal colonColon can’t relax in this area

Failure to pass meconium in first 24 hours

Accumulation of stool proximal to defect

Can present in older kids as severe constipation

“Blast” sign: digital rectal exam causes explosive release of stool

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15
Q

Peds Diseases: Hemolytic Uremic Syndrome

Triad

Populatuion

Symptoms

A

Triad of hemolytic anemia, thrombocytopenia, uremia

One of the most common cause of acute renal failure in kids less than 4

Most common cause in E. coli O157:H7 (in bad hamburger meat classically)

Sx: typically have a preceding URI or gastroenteritis; dehydration, edema, petechiae, hepatosplenomegaly, oliguria

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16
Q

Adult: Acute Diarrhea

Most common cause

Associated factors

Symptoms

A

Most commonly viral

Most common bacterial gastroenteritites: Salmonella, campylobacter

Common associations:

Traveler: Enterotoxigenic E. Coli

Camping: Giardia, entamoeba

HIV: Cryptosporidium

Undercooked beef with bloody urine: E. coli O157:H7

Cruise: Norwalk virus

Bloody diarrhea: invasive organisms like campylobacter, shigella, salmonella

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17
Q

Adult: GERD

What is it

Symptoms

Associated symptoms

Other diagnosis

A

Reflux of gastric contents into esophagus

Sx: burning post-prandial chest pain, worse with laying down

Ass’d cough, sour taste in throat, hoarseness

On differential diagnosis of chest pain (including killers like MI, PE, etc.)

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18
Q

Adult: Irritable Bowel Syndrome

Criteria

Absent symptoms

Correlation Symptoms

A

Rome CriteriaRecurrent abdominal pain or discomfort for at least 3 days/month for 3 months with 2 of following:

Relief with defecation

Change in stool frequency

Change in stool form (diarrhea/constipation)

None of the alarm symptoms of inflammatory bowel syndrome

No bloody diarrhea or weight loss

Can be correlated with stress

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19
Q

Adult: Hiatal Hernia with Esophagitis

What is it

Similar to

Symptoms

Treatment

A

Part of the stomach passes though the esophageal hiatus leading to loss of the “functional” LES

Similar symptoms to GERD

Can incarcerate like any hernia: Sx: sudden vomiting, pain, complete dysphagia

Tx is surgical

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20
Q

Adult: Duodenal Ulcer

Cause

Symptoms

A

Almost always 2/2 H. pylori

Can cause GI bleed (hematemesis, melena, hematochezia, anemic sx) or perforate (presents like an acute abdomen)

Anterior more likely to perf, posterior more likely to hemorrhage

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21
Q

Adult: Crohn’s Disease and Ulcerative Colitis

comparison

A

This will be high yield for years to come (know the differences between these two)

Some high yield differences

Crons

  • Entire GI tract involved (mouth to anus)- perianal skin tags, mouth ulcers, etc.
  • Fistula likely
  • Extraintestinal symptoms common
  • Diarrhea less frequently bloody

UC

  • Only colon affected
  • Fistula not likely
  • Extraintestinal symptoms common
  • Diarrhea more frequently bloody
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22
Q

Adult: Stomach Cancer

Symptoms

A

Vague sx: wt loss, early satiety, dysphagia, epigastric pain

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23
Q

Adult: Diverticular disease

symptoms

diverticulosis vs. diverticulitis

A

Outpouching of colon (most commonly sigmoid)

Diverticulosis- Presence of diverticula in the colon

Most common symptom- GI bleed (hematochezia, melena)

Diverticulitis- Inflammation of a diverticulum

Most common symptoms- LLQ pain, anorexia, N/V, diarrhea/constipation

Common in older population

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24
Q

Adult: Colon Cancer

Main symptoms

Symptoms

A

Any adult with anemia has colon cancer until proven otherwise!

Sx: Depends on location- Bleeding sx more likely if proximal, obstructive sx or change in stool caliber more likely with distal lesions

Look at risk factors on P. 492 and Screening on P. 525

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25
Adult: Hepatitis Most common cause Symptoms Leads to
Most commonly 2/2 viral infection, alcohol, drugs, toxins Sx: Asx → jaundice, anorexia, clay colored stools, abdominal pain Can be acute or chronic and can lead to cirrhosis
26
Adult: Cirrhosis What is it Associated with Symptoms
Fibrosis and alteration of liver architecture Nodular; enlarged, then shrunken Most commonly caused by hep C and alcohol Sx of decreased liver function (e.g. problems with coagulation), portal hypertension (e.g. ascites, esophageal varices, caput medusa, etc.)
27
Adult:Hepatocellular Carcinoma Arises from cirrhosis Symptoms
Most commonly arises 2/2 cirrhosis Similar liver symptoms to other liver pathology: jaundice, anorexia, clay colored stools, abdominal pain
28
Adult: Cholelithiasis Symptoms
Presence of stones in the gall bladder Can be Asx → biliary colic (recurring postprandial RUQ abd pain that may last a couple hours then resolve)
29
Adult: Cholecystitis What is it Symptoms
Inflammation of gall bladder, most commonly 2/2 obstruction of cystic duct with a gall stone Sx: Persistent RUQ pain, fever, anorexia, N/V
30
Nonalcoholic Fatty Liver Disease What is it Associated with Symptoms What it can lead to
Spectrum of liver disease from steatosis (reversible) to cirrhosis (nonreversible) (Obviously) not related to alcohol intake Common in obese people with metabolic syndrome Same liver symptoms as many of the above diseases: jaundice, anorexia, clay colored stools, abdominal pain; However, most commonly asx until it has progressed significantly Can lead to hepatocellular carcinoma
31
Adult: Acute Pancreatitis Most common cause alcohol and gall stones Symptoms Labs Importance?
Most common causes: alcohol and gall stones Sx: epigastric pain radiating to the back, esp after a fatty meal Labs: amylase, lipase (lipase more sensitive) Can be deadly
32
Pyelonephritis What is it Risks Symptoms
Infection of the kidney; most commonly ascending Risks: diabetes frequent UTIs, GU abnormality, sexual activity Sx: Dysuria; fever, **chills, flank pain/CVA tenderness** (vs. cystitis)
33
Chronic pancreatits Symptoms
Same causes as in acute pancreatitis; alcohol most common Sx: Constant unremitting abd pain, weight loss, steatorrhea
34
Spleen laceration/rupture Trauma relations Symptoms
Most commonly injured organ in abdominal trauma Sx: LUQ pain radiating to L shoulder (Kehr sign), hypovolemic sx Spleen bleeds a lot
35
Acute glomerulonephritis What is it Symptoms
Often 2/2 immune complexes Many causes including immune mediated, post-streptococcal (kid with strep throat) Sx: flank pain, hematuria/tea colored urine, HTN, edema (esp. periorbital)
36
Hydronephrosis Symptoms Pogression
Dilation of renal pelvis and calyces due to obstruction of urine flow Most are asx but can cause renal colic and hematuria if an acute obstruction Can impair renal function eventually
37
Renal Abscess Symptoms
Sx of pyelonephritis that do not get better with antibiotics like pyelo does
38
Renal Calculi More commonly in Symptoms Can lead to what
More common in men Sx: flank pain radiating to groin, fever, dysuria, hematuria Can lead to pyelo
39
Acute renal failure Labs Locations Urine output
Absolute rise in serum Cr of 0.5 – 1.0 (though there are other diagnostic criteria) Prerenal (e.g. hypovolemia), renal (e.g. acute glomerulonephritis), or postrenal (e.g. obstruction) Think about other sx: if pt has signs of hypovolemia (postural dizziness, fatigue, etc.) think prerenal, and so on Can have normal urine output or be anuric/oliguric Sx will be related to underlying cause (often Asx)
40
41
Production of the blood
* **Liver** Forms blood cells by week 6 Forms glycogen by week 9 Forms bile by week 12 **Spleen** Produces insulin by week 12 Forms blood in fetus and first year of life; afterwards, lymphatic function **Kidne** * Make urine by 12 weeks * Development of new nephrons stops at 36 weeks; afterwards grows via hypertrophy * GFR increases linearly in childhood to adult rate
42
When is GI adapted to extrauterine life When it is fully developed
GI tract capable of adapting to extrauterine life by 36 weeks, but not fully developed functionally until 2-3y
43
Abdominal changes during pregnancy Abdominal wall/skin
Rectus abdominis separates, which can lead to diastasis recti (persistent separation of rectus muscles) after pregnancy Skin changes: Striae, linea nigra (midline line of pigmentation) develops
44
Abdominal changes during pregnancy Intestinal tract
Decreased LES pressure + Decreased peristaltic velocity in esophagus→ Reflux Constipation 2/2 increased GI transit time
45
Abdominal changes during pregnancy Gallbladder
Decreased emptying of GB + change in bile content → increased incidence of cholelithiasis
46
Abdominal changes during pregnancy Kidneys/Bladder
Enlarged uterus can lead to urinary stasis Renal function most efficient in lateral recumbent position (Less compression of aorta and IVC) Uterus pushes on bladder → urinary frequency
47
Abdominal changes during pregnancy Appendix
Displaced upward and laterally… Don’t let the location of appendicitis in pregnant women fool you!
48
Abdominal changes in the elderly
Motility affected most (vs. secretion/absorption) Decreased liver function
49
Inspection on GI/GU exam
* **Striae** * **Scars** * **Umbilical lymph node**- “Sister Mary Joseph Nodule” can mean metastatic pelvic/abdominal cancer * **Contour** * Rounded: e.g. overweight adult * Flat: e.g. adult with six pack * Scaphoid: e.g. very thin adult * \*Clinical Pearl: distended abdomen + hypoactive bowel sounds+ no pain or mass+ Pt on diuretics or steroids → Think hypoK+ * **Ask pt to Valsalva** → Can cause ventral hernias to protrude if present
50
Normal frequency of bowel sounds
5-35/min
51
Loud, long gurgles (stomach growling)
“Borborygmi”
52
Increased sounds GI
gastroenteritis, early intestinal obstruction, or hunger
53
High-pitched GI
“tinkling”: possible early obstruction
54
Additional sounds GI Bruits Venous hum
Listen for in aorta, renal, iliac, and femoral arteries if concerned (e.g risk factors for atherosclerosis, HTN, etc.) 2/2 increased collateral circulation between the portal and systemic venous systems
55
Normal bottom border of liver Normal upper border of liver
3 cm below the costal margin 5-7th intercostal
56
Changes in lower costal margin of liver
Abnl can be caused by liver enlargement or downward displacement of diaphragm by pulmonary disease
57
Changes in upper border of liver
Higher: can be 2/2 ascites or abdominal mass Lower: can be 2/2 liver atrophy or downward displacement
58
Murphy’s Sign
Gall bladder Deeply palpate RUQ below costal margin, have pt take a deep breath out and then in → If positive, when inflamed GB touches hand on inspiration, pt will abruptly halt inspiration
59
Assessing ascites: Shifting Dullness
Identify borders of tympany and dullness (ascites settles to dependent part of abdomen pushing tympanytic bowel to the non-dependent part) Then have pt lie on one side → Borders of dullness should shift to the dependent side as the ascites follows gravity downwards
60
Assessing ascites: Fluid Wave
Have pt or assistant place edge of hand firmly along the midline of the abdomen Place your hands on both sides of the abdomen and strike one side sharply with your fingertips → If ascetic, should feel pressure wave hit your other hand
61
Aaron sign
Pain in epigastric region with palpation of McBurney’s point Appendicitis
62
Balance sign
Fixed dullness to percussion in the left flank and dullness in the right flank that disappears on change in position Peritoneal irritation
63
Blumberg sign
Rebound tenderness Peritoneal irritation
64
Cullen sign
Periumbilical ecchymosis Hemoperitoneum, pancreatitis, ectopic pregnancy
65
Dance sign
Absent bowel sounds in the RLQ Intussusception
66
Grey Turner sign
Flank Ecchymosis Hemoperitoneum, pancreatitis
67
Kehr sign
Abdominal pain radiating to left shoulder 2/2 diaphragm irritation Spleen rupture, renal calculus, ectopic pregnancy
68
Markle sign
: Pt stands and toes and then abruptly lands on heels causing abd pain Peritoneal irritation
69
McBurney sign
Rebound at McBurney’s point (2/3 of distance from umbilicus to ASIS) Appendicitis
70
Murphy’s sign
Cholecystitis
71
Romberg-Howship
Pain down medial aspect of the thigh to the knees Stangulated obturator hernia
72
Rovsing sign
RLQ pain worsened with LLQ palpation Appendicitis
73
Dunphy’s sign
Physician surreptitiously bumps into the bed → Positive if it causes abdominal pain in the patient
74
Hamburger sign
Pt with appendicitis should not want to eat, so ask if they are hungry (80% sensitive!)
75
Psoas sign
Pt lays supine; ask pt to raise leg, flexing at the hip, while you push downward → Positive if it reproduces the RLQ pain; can indicate retrocecal appendix
76
Obturator sign
Flex right leg at left hip and knee to 90 degrees and physician rotates the leg medially and laterally → Positive if it reproduces the RLQ pain; can indicate retrocecal appendix
77
Rebound Tenderness GI
Hold hand with fingertips extended at a 90 degree angle to the abdomen and press deeply away from the area of discomfort, then rapidly withdraw your hand If pain is worse when your hand is pulled away, then + for rebound tenderness = peritoneal irritation
78
Infant Physical: Umbilical Cord
Thick: well nourished Thin: not well nourished Should have 2 arteries and 1 vein Umbilical hernias are common and generally close spontaneously by 1-2y
79
Infant Physical: Masses
Olive shaped, RUQ = pyloric stenosis Sausage shaped L or RUQ = Intussusception Midline suprapubic mass = Hirschsprung disease
80
Infant Physical: Enlarged Liver
Common in newborn with mom with poorly controlled DM during pregnancy