More Krebs Cycle Help Flashcards

1
Q

In which steps are NADH produced

A

3 steps produce NADH.

Isocitrate –> Alpha ketoglutarate
catalyzed by: isocitrate dehydrogenase

Alpha ketoglutarate –> Succinyl CoA
catalyzed by: alpha ketoglutarate dehydrogenase

Malate–>oxaloacetate
catalyzed by: Malate Dehydrogenase

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2
Q

Which steps in the Krebs Cycle produce CO2?

A

2 steps:

Isocitrate –> Alpha ketoglutarate
catalyzed by: isocitrate dehydrogenase

Alpha ketoglutarate –> Succinyl CoA
catalyzed by: alpha ketoglutarate dehydrogenase

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3
Q

Which intermediate in the Krebs cycle is used for substrate level phosphorylation?

A

the high energy molecule Succinyl CoA

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4
Q

What REACTION in the krebs cycle produces GTP?

A

Succinyl CoA—-> Succinate
catalyzed by: Succinyl-CoA synthetase

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5
Q

Which reaction in the Krebs cycle produces QH2 (or FADH2)

A

Succinate —> Fumurate
catalyzed by: Succinate dehydrogenase

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6
Q

Each QH2 molecule can produce _____ ATP

A

2

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7
Q

Each NADH molecule can produce ______ ATP

A

3

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8
Q

Each GTP molecule can produce ______ ATP

A

1

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9
Q

How many NADH, QH2, AND GTP are produced in the Krebs cycle?

A

3 NADH
1 QH2
1 GTP

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10
Q

For every molecule of acetyl-coA invested in the Krebs Cycle, how many CO2 are released?

A

2

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11
Q

The Krebs cycle operates in the ____ of the mitochondria, while the ETC operates in the ____ of the mitochondria

A

Krebs cycle operates in the MATRIX of the mitochondria while the ETC operates in the MEMBRANE of the mitochondria

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12
Q

Name the 4 dehydrogenase enzymes

A

-isocitrate dehydrogenase
-alpha ketoglutarate dehydrogenase
-succinate dehydrogenase
-Malate dehydrogenase

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13
Q

Name the enzymes in order, starting with the enzyme that catalyzes the formation of citrate from oxaloacetate and acetyl-CoA

A
  1. citrate synthase
  2. aconitase
  3. isocitrate dehydr.
  4. a ketoglutarate dehydr.
  5. Succinyl-CoA Synthetase
  6. Succinate dehydr.
  7. Fumarase
  8. Malate dehydr.
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14
Q

Name the intermediates in order starting with citrate

A
  1. Citrate
  2. Isocitrate
  3. a ketoglutarate
  4. succinyl-CoA
  5. Succinate
  6. Fumarate
  7. Malate
  8. Oxaloacetate
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