Mood Stabliziers Flashcards
1
Q
2 groups of drugs for mood stabilizing?
A
Anti seizure agents
Misc. like lithium
2
Q
2 MOA of lithium?
A
Blocks calcium dependent NE and DA release
Inhibits G protein synthesis
3
Q
Clinical use for lithium, 2 things?
A
Acute and prophylactic treatment of Bi polar
Augmentation in unipolar depression
4
Q
What are 6 common side effects of lithium?
A
Polyuria Tremor Mental confusion Thyroid goiter Leukocytosis Seizures and serotonin syndrome
5
Q
3 drug interactions impacting sodium potassium for lithium?
A
Diuretics, ACEI, and NSAIDs
6
Q
What is the therapeutic windows for lithium?
A
Very narrow
7
Q
Clinical use for Divaproex?
Carbamazepine?
Lamotrigine?
A
Acute Bipolar 1
Acute and maintenance of Bipolar 1
Maintenance of Bipolar 1 and 2
8
Q
Drug to drug interaction for carbamazepine?
A
CYP 450 inducer