Mood Disorders Flashcards
Define Mood Disorder
1 or more major depressive episodes
Onset of MDD
usually in mid 20s
Male-to-female ratio for mood disorder
1:2
Symptoms of depressive episode
Sleep; Interest(decreased); Guilt; Energy (decreased); Concentration (decreased); appetite or weight; Psychomotor agitation or retardation; Suicide ideation
Requirement for MDD
depressed mood or anhedonia and 5 more S&S from SIG E CAPS for 2-week period
Atypical Depression
weight gain, hypersomnia, and rejection sensitivity
Postpartum Depression
Occurs within 1 month postpartum, psychotic symptoms are common
Seasonal Depression
Depressive episodes during a particular seasons, usually in the winter. Responds well to light therapy +/- antidepressants
Double Depression
major depressive episode in a patient with dysthymia. Has poorer prognosis that MDE alone
Pharmacotherapy Timeframe for MDD
effective in 50-70% patient, allow 2-6weeks to take effect; treat for 6+ months
Pharmacotherapy for MDD (drug classes)
SSRIs, Atypicals, SNRIs, TCAs, MAOIs
Best treatment combination for MDD
Pharmacotherapy + Psychotherapy
When to use ECT
Refractory depression or psychotic depression, or if rapid improvement in mood is needed; also used for intractable mania and psychosis
Adverse Effects of ECT
postictal confusion, arrhythmias, HA, and anterograde amnesia
TCA toxicity
3 C’s; Convulsions, Coma, Cardiac Arrhythmias
Medical conditions that can cause mood disorder
hypothyroid, parkinson, CNS neoplasm, ceoplasms, stroke (esp ACA), dementias, parathyroid