Anxiety Disorders

Question 1

Uncontrollable, excessive anxiety or worry about multiple activities or events leading to significant impairment or distress.

Answer 1

Generalized Anxiety DIsorder

Question 2

Clinical Onset of GAD

Answer 2

Early 20s

Question 3

Name ~3 somatic symptoms associated with GAD

Answer 3

Restlessness, fatigue, difficulty concentrating, irritability, muscle tension, disturbed sleep

Question 4

Short Term Therapy for GAD

Answer 4

Benzodiazepines, then taper these off as soon as long term tx is established

Question 5

Long Term Therapy for GAD

Answer 5

Lifestyle Changes, Psychotherapy, Medications (SSRIs are first line, venlafaxine, buspirone)

Question 6

List of SSRIs

Answer 6

Fluoxetine, Sertraline, Paroxetine, Citalopram, Escitalopram

Question 7

SSRI indication

Answer 7

First-line for GAD, OCD and PTSD

Question 8

SSRI, major side effects

Answer 8

Nausea, GI upset, somnolence, sex dysfx, agitation

Question 9

Buspirone Indication

Answer 9

GAD, OCD, PTSD

Question 10

Buspirone, major side effects

Answer 10

Seizures with chronic use; No tolerance, dependence, or withdrawal

Question 11

Beta-blockers Indication

Answer 11

Performance Anxiety, PTSD

Question 12

Beta-blockers, major side effects

Answer 12

Bradycardia, hypotension

Question 13

Benzodiazepine Indication

Answer 13

Anxiety, insomnia, alcohol withdrawal, muscle spasm, night terrors, sleepwalking

Question 14

Benzodiazepine, major side effects

Answer 14

Decreased sleep duration; risk of abuse, tolerance, and dependence; disinhibition in young or old patients; confusion

Question 15

Flumazenil MoA

Answer 15

Competitive antagonist at GABA receptor

Question 16

Flumazenil Indications

Answer 16

Antidote to banzeodiazepine intoxication

Question 17

Flumazenil, major side effects

Answer 17

Resedation; nausea, dizziness, vomiting and pain at injection site