Mood Disorders Flashcards
What is the definition of Major Depressive Disorder (MDD)?
MDD is a condition where at least 2 weeks of low mood predominate, resulting in significant distress or impairment in functioning.
What is the prevalence of Major Depressive Disorder in the population?
5% of the population.
What is the gender ratio for Major Depressive Disorder?
The ratio of females to males is 2:1.
List the main symptoms required for a diagnosis of MDD.
Depressed mood most of the day nearly every day, Sleep disorder, Interest deficit, Guilt, worthlessness, hopelessness, Energy deficit, Concentration deficit, Appetite disorder (increase or decrease), Psychomotor retardation/agitation, Suicidality or recurrent thoughts of death.
What screening tools are used for diagnosing MDD?
K10, psychiatric interview, and mental status examination (MSE).
What are some common comorbidities associated with MDD?
Other psychiatric disorders, neurological disorders, endocrine disorders, metabolic disorders, and substance misuse.
What is the definition of Dysthymia?
Symptoms of depression lasting at least 2 years, less severe than MDD.
What is the prevalence of Dysthymia in the population?
1%.
What are the diagnostic criteria for Dysthymia?
Depressed mood for most of the day, more days than not for more than 2 years, plus two or more of the following: appetite disorder, concentration deficit, hopelessness, energy deficit, worthlessness, and sleep disorder.
What are some specifiers for Dysthymia?
Mixed features, melancholic features, atypical features, psychotic features, catatonia, peripartum onset, and seasonal pattern.
What are first-line treatments for Dysthymia?
SSRIs such as Sertraline, Citalopram, Escitalopram, Paroxetine, and Fluoxetine.
What characterizes Melancholic Depression?
Persistent and severe depression with a loss of pleasure in all or almost all activities and a lack of reactivity to usual pleasurable stimuli.
What are the symptoms of Melancholic Depression?
Profound despondency, despair, depression worse in the morning, early-morning awakening, marked psychomotor agitation, significant anorexia or weight loss, and excessive or inappropriate guilt.
How is Melancholic Depression typically treated?
Treatment is similar to MDD, with SNRIs being more efficacious.
What distinguishes Atypical Depression from MDD or Dysthymia?
Improvement in mood in response to positive events.