Mood Disorders Flashcards

1
Q

Screen for Major Depresive DO (MDD)

A

PHQ-9, PHQ-2

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2
Q

How is MDD different than Bipolar?

A

MDD has NO MANIA

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3
Q

For MDD, you must R/O _____ and _____

A

Bipolar
Hypothyroidism

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4
Q

Persistent Depressive Disorder lasts:
___yr+ (Adult)
____yr+ (Child)

A

2yr+ (Adult)
1yr+ (Child)

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5
Q

1st line Tx for MDD and Persistent Depressive DO

MDD = Major Depressive DO

A

1 Psychotherapy + SSRI (Lexapro, Zoloft)

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6
Q

MDD and Persistent Depressive DO Tx Resistant

A
  • ADD 2nd Gen Antipsychotic, Lithium, 2nd antidepressant from diff class, Thyroid hormone
  • TMS
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7
Q

MDD and Persistent Depressive DO (SEVERE Tx)

A
  • ECT (Electroconvulsive therapy)
  • Esketamine, Ketamine

ECT is 1st line if suicidal, severe wt loss, real bad

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8
Q

Tx for Mod/Severe Premenstrual Dysphoric DO

A
  • CBT
  • SSRIs
  • COCs or GnRH Agonists
  • Last resort -> Bil (salping)oophorectomy
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9
Q

______ DO is when children have chronic irritability, anger, or tantrums

A

Disruptive Mood Dysregulation DO

Can last into adulthood but must be Dx as a child

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10
Q

Disruptive Mood Dysregulation DO
* Lasts: ___yr+
* Peds onset: ___ - ___yo
* Dx: ___ - ____yo

A
  • Last: 1yr+
  • Peds onset: 6-10yo
  • Dx: 6-18yo

Must start b/w 6-10yo but can be Dx anytime from 6-18yo (peds only).

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11
Q

Disruptive Mood Disregulation DO Tx

A
  • # 1 Psychotherapy
  • Off-label meds
  • Parent Education
  • Refer to peds psychologist/psychiatrist
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12
Q

Bipolar is MC in which age groups?

A

15-24yo
45-54yo

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13
Q

Bipolar I Manic episodes last for _____

A

1+ week

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14
Q

Bipolar II Hypomanic episodes last for _____

A
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15
Q

1st line Tx for Bipolar DEPRESSION

A

Monotherapy 2nd Gen “Atypical” Antipsychotic (Quetiapine or Lurasidone)

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16
Q

Tx for REFRACTORY Bipolar Depression

A

ECT

rapid response if real bad

17
Q

Bipolar I pts NEED and anti-depressant + _______

A

Mood Stabilizer

Antidepressants can unmask Bipolar bc theyre no longer depressed and have the potential to become HIGHLY MANIC

18
Q

1st line Tx for Bipolar Mania/Hypomania

A
  • Mood stabilizer (Lithium, Valproate)
  • Antipsychotic (Ariprazole, Asenapine, Cariprazine, Quetiapine, Rispiridone)
19
Q

Tx for poorly controlled or Severe Bipolar Mania/Hypomania

A

Mood stabilizer + Antipsychotic

21
Q

Tx for Bipolar Mania/Hypomania if Tx Resistant or Preg

A

ECT

Mono or in combo with other Tx options

21
Q

1st line Tx for Bipolar in PEDS

A

Pharmacotherapy + Psychotherapy

very unique that pharmacotherapy is 1st line before therapy

22
Q

1st line Tx for Bipolar Depression in PEDS

A

Choose 1:

  • Lurasidone
  • Alt 2nd Gen Antipsychotic + SSRI

I guess Lurasidone is the only 2nd gen antipsychotic that can be taken w/o SSRI in peds for this

23
Q

Tx for Bipolar Depression (Tx Resistant) in PEDS

A

Lithium, Lamotrigine, or Omega-3 Fatty Acids

24
Q

Tx for Bipolar Depression (Tx Resistant) in PEDS

A

Lithium, Lamotrigine, or Omega-3 Fatty Acids

25
Q

1st Line Tx for Bipolar in PEDS

A

Pharmacotherapy + Psychotherapy

unique that pills is 1st line before therapy

26
Q

1st Line Therapy for Bipolar Depression in PEDS

A

Pick 1:
* Lurasidone
* Alt 2nd gen antipsychotic + SSRI

I guess Lurasidone is the only “Atypical” that can be taken w/o an SSRI in peds for this

27
Q

Tx for Bipolar Depression in PEDS if:
* Tx Resistant ->
* Partial Response ->
* Tx Refractory

A
  • Tx Resistant -> Lithium, Lamotrigine, or Omega-3 Fatty Acids
  • Partial Response -> ADD Lithium, Lamotrigine, or Omega-3 Fatty Acids
  • Tx Refractory -> Lithium + (Lamotrigine or Antidepressant), ECT, Bright Light Therapy
28
Q

Order ___ prior to giving Lithium to Peds

A
  • BUN, Creat
  • E-
  • TSH
  • ECG
  • Urine Preg

  • Measure [Lithium] after 1st week of taking
  • Stable dose -> repeat initial WU q 3-6mo
29
Q

1st Line Tx for Bipolar Mania/Hypomania in PEDS

A

2nd gen antipsychotic +/- Lithium

30
Q

Tx for Bipolar Mania/Hypomania in PEDS if
* Tx Resistant ->
* Partial Response or Refractory ->

A
  • Tx Resistant -> try diff antipsychotic
  • Partial Response or Refractory -> antipsychotic + LITHIUM
31
Q

Tx for Bipolar Mania/Hypomania in PEDS if Refractory to 8-10med trials

A
  • Cloazapine
  • ECT
32
Q

Tx for Bipolar Mania **W/Mixed or Psychotic Features **in PEDS

A

2nd Gen Antipsychotic

NO LITHIUM?

33
Q

Suicide Attempt Tx:
Give ___ to prevent suicide

A

Lithium

34
Q

Suicide Attempt Tx for severe depression

A

ECT

35
Q

Suicide Attempt Tx: Alterantive for Lithium to prevent suicide

A

Ketamine/Esketamine

36
Q

______ Mood DO = Chronic mood instability W/O Extreme mood episodes

A

Cyclothymic

Not Hypomanic enough for Bipolar II. Not Depressed enough for MDD

37
Q

Cyclothymic Mood DO Lasts:
____yr+ (Adult)
____yr+ (Peds)

A

2yr+ (Adult)
1yr+ (Peds)

Ss for half the time.
Max: 2mo in b/w episodes

38
Q

Cyclothymic Mood DO Tx

A

NO FDA approved meds
* #1 Mood Stabilizer
* 2nd Gen “Atypical” Antipsychotics +/- Mood Stabilizer
* CBT