Mood Disorders

Question 1

Ebstein’s anomaly in newborns is a defect where and related to which medication? Is it cyanotic or not?

Answer 1

Tricuspid valve (and RV) defect
Lithium (and benzodiazepine) use
Yes it is cyanotic

Question 2

Discontinuation of antidepressants can lead to side effects, mnemonic FINISH stands for what symptoms?

Answer 2

F lu like symptoms
I nomnia 
N ausea 
I mbalance
S ensory disturbance 
H yperarousal

Question 3

CBT addresses maladaptive cognitions/behaviours, typically how many sessions are given over how long roughly?

Answer 3

16-20 sessions

Over 3-4months

Question 4

The SSRI Paroxetine carry’s what risk in pregnancy? SSRIs used in the 3rd trimester also carry a risk of what?

Answer 4

• congenital malformations

- pulmonary hypertension

Question 5

Delusions are what?

Answer 5

Fixed held abnormal beliefs (firmly held despite alternative explanations)

Question 6

“False perception without an external stimulus” is the definition of what?

Answer 6

Hallucinations

Question 7

Passivity phenomena in schizophrenia refer to what?

Answer 7

-perceiving ones thoughts/feelings/actions are being controlled by an outside force

Question 8

Haloperidol (typical antipsychotic) acts mainly on which receptors?
Name 3 SEs:

Answer 8

• D2 receptors
• movement disorders, dry mouth, blurred vision
• postural hypotension, impotence
• sedation, weight gain

Question 9

Atypical antipsychotics like clozapine, risperidone.. have less extra pyramidal SEs but more what?

Answer 9

More incidence of metabolic side effects

Question 10

What is the biggest risk with the atypical antipsychotic Clozapine? What monitoring is needed? And
What is it reserved for?

Answer 10

• risk of agranulocytosis, do weekly FBC for first 18weeks, then fortnightly then monthly ongoing
• reserved for treatment resistant schizophrenia