Mood Disorders Flashcards
define bipolar affective disorder (BPAD)
a mental disorder characterised by periods of depression and periods of elevated mood (mania)
triggers of manic episodes in BPAD
stressful life events
physical illness
illicit substance misuse
clinical features of depression periods in BPAD
withdrawn behaviour tearful low mood poor sleep anhedonia self-harm thoughts/actions
clinical features of manic episodes in BPAD
elevated mood irritability impulsive and dangerous decisions little regard to consequence reduced sleep need pressured speech flight of ideas
diagnostic criteria for BPAD by DSM
at least one episode of manic or hypomanic state and one major depressive episode
DSM definition of mania
distinct period of abnormal and persistently elevated, expansive or irritable mood lasting >1wk with three key symptoms
key symptoms included in DSM definition of mania
elevated self-esteem reduced sleep need increased speech rate flight of ideas easily distracted increased interest in goals/activities psychomotor agitation increased pursuit of 'dangerous' activities
DSM definition of hypomania
an episode of mania severe enough to cause marked impairment in social or occupational function with NO psychotic features
DSM definition of major depressive episode
sudden or new onset of at least 4 key symptoms for minimum of 2wks
key symptoms included in DSM definition of major depressive episode
changes in appetite, sleep, weight or motor activity
decreased energy
feelings of worthlessness or guilt
trouble thinking, concentrating or making decisions
thoughts of death
suicidal plans or attempts
acute management of mania WITH agitation in BPAD
IM neuroleptic or benzodiazepine
urgent secure unit admission
acute management of mania WITHOUT agitation in BPAD
oral monotherapy with antipsychotic
sedation and lithium added if necessary
acute management of depression in BPAD
mood stabiliser +/- atypical antipsychotic +/- antidepressant
chronic management of BPAD
lithium
second line: valproate
psychological therapy (e.g. CBT or interpersonal)
chronic management of BPAD if treatment resistant
antipsychotic + anticonvulsants