Mood Disorder: Major Depression

Question 1

a pervasive and sustained emotion or feeling
tone which influences a person’s behavior as well as
his or her perception of the world.

Answer 1

Mood

Question 2

3 components of mood

Answer 2

Feeling
Perception
Bhvr

Question 3

external expression of mood

Answer 3

Affect

Question 4

currently known as

schizophrenia or psychotic disorders

Answer 4

Dementia Praecox

Question 5

How can chronic depression lead to suicide attempts biologically?

Answer 5

chronicity may be attributed to the loss of
neuronal connections. The hippocampus also
shrinks, thus the suicide attempts.

Question 6

Monoamines involved in depression

Answer 6

Dopamine
Norepinephrine
Serotonin

Question 7

Most prominent neurotransmitter involved in depression

Answer 7

5 HIAA (5- hydroxyindole acetic acid)

Question 8

What is the neurotrophic theory of depression

Answer 8

This believes that main cause of depression is stress where there’s increase in production of cortisol which is deadly to the spines of neurons, in the long run it can lead to shrinkage of hippocampus and eventually depression

Question 9

This is also called the fertilizer of the brain

Answer 9

BDNF

Question 10

In the immune cytokine theory it believes that increased cortisol will stop production of what substance?

Answer 10

Brain derived neurotrophic factor

Question 11

Personalities more prone to depression

Answer 11

OCD, histrionic, borderline

Question 12

Most powerful predictors of the onset of depressive episode

Answer 12

Recent stressful events

Question 13

4 key points in the psychodynamic theory

Answer 13

1. Disturbances in the infant mother relationship during oral phase
2. Can be linked to real or imagined loss
3. Introjection of the departed objects is a defense mechanism
4. Feelings of anger are directed inward

Question 14

Cognitive triad of depression

Answer 14

Negative: self perception
View of the future
View of the environment

Question 15

Life event most associated with the development of

depression:

Answer 15

loss of parent before the age of 11

Question 16

Environment stressor most associated with onset of

depression is

Answer 16

Loss of a spouse

Question 17

Duration of depression before it can be considered MDD

Answer 17

2 weeks

Question 18

3 core symptoms of depression

Answer 18

Depressed mood of the day almost every day
Loss of interest or pleasure from activities that are normally enjoyable
Decreased energy or easily fatigued

Question 19

What question would you ask for you to rule out bipolar d/o?

Answer 19

Did you before have episodes of
extremely elevated and irritable mood, increased
activity, extreme talkativeness, extreme decreased
need for sleep?

Question 20

The key distinction between mild and moderate-severe
depression is iThe key distinction between mild and moderate-severe
depression is impairment in a person’s daily activities

Answer 20

The key distinction between mild and moderate-severe

depression is impairment in a person’s daily activities

Question 21

T or F antidepressants are the first line of treatment in all age group

Answer 21

False: <12: do not prescribe antidepressants
>12: do not consider antidepressants as 1st line
Adults: treat medical condition first before anti_D

Question 22

Serious and rare side effects of amitriptyline

Answer 22

Cardiac arrhythmia

Question 23

Mnemonic for depression

Answer 23

SIGECAPS
S: Sleep changes
I: Interest (loss)
G: Guilt
E: Energy
C: Cognition/concentration
A: Appetite
P: Psychomotor
S: Suicide/ death preocp.

Question 24

Refers to the presentation of children with persistent
irritability and frequent episodes of extreme behavioral
dyscontrol

Answer 24

DISRUPTIVE MOOD DYSREGULATION DISORDER

Question 25

Children with disruptive mood dysregulation disorder eventually develop what

Answer 25

Unipolar depression or anxiety disorder

Question 26

Persistent depressive d/o may be considered if the mood disturbance continues for how long?

Answer 26

for at least 2 years in

adults or 1 year in children.

Question 27

Depressive disorder that begins following ovulation and
remits within a few days of menses with marked impact
on functioning

Answer 27

PREMENSTUAL DYSPHORIC DISORDER