MONONUCLEOSE Flashcards

1
Q

DNA OU RNA

A

DNA

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2
Q

AGENTE ETIOLOGICO - FAMILIA

A

HERPESVIRIDAE

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3
Q

AGENTE ETIOLOGICO - GENERO

A

EPSTEIN-BARR

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4
Q

TRANSMISSAO

A

DOENCA DO BEIJO

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5
Q

PATOGENIA

A
  1. CELS EPITELIAIS ORAIS
  2. ESTRUTURAS CONTIGUAS (GLANDULAS SALIVARES)
  3. VIREMIA = INFECCAO DOS LINFOCITOS B NO SANGUE PERIFERICO
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6
Q

PRIMEIRO SINTOMA

A

FARINGITE

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7
Q

CARACTERISTICA DA TRANSMISSAO VIRAL

A

O VIRUS PODE SER ELIMINADO DE FORMA INTERMITENTE COMO RESULTADO DA REATIVACAO VIRAL

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8
Q

RELACAO ENTRE EBV E

A

NEOPLASIAS (CARCINOMA NASOFAR; BURKITT; HODGKIN; ETC)

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9
Q

INCUBACAO

A

LONGA >30 DIAS

MAIS CURTO EM CRIANCAS

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10
Q

SINTOMAS

A

FADIGA
FEBRE
DOR ABDOMINAL
MIALGIA

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11
Q

90% DOS PACIENTES APRESENTA

A

LINFADENOPATIA GENERALIZADA

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12
Q

50% DOS PACIENTES APRESENTA

A

ESPLENOMEGALIA

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13
Q

10% DOS PACIENTES APRESENTA

A

HEPATOMEGALIA

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14
Q

OROFARINGE

A

INDISTINGUIVEL DA FARINGITE ESTREPTOCOCICA

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15
Q

LINFADENOPATIA SUGESTIVA

A

EPITROCLEAR

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16
Q

SINAL DE HOAGLAND

A

EDEMA PALPEBRAL

17
Q

EDEMA PALPEBRAL

A

SINAL DE HOAGLAND

18
Q

PORCENTAGENS DO EXANTEMA

A

MACULOPAPULAR EM 3-15%

PRESENTE EM 80% DOS PACIENTES QUE FAZEM USO DE AMOX OU AMPI

19
Q

ACHADOS LAB

A

ANEMIA HEMOLITICA COM COOMBS POSITIVO (ANEMIA APLASICA RARA)
TROMBOCITOPENIA
LEUCO COM ATIPICOS (TCD8+)

20
Q

IDENTIFICACAO DE ANTICORPOS HETEROFILOS

A

AGLUTINAM HEMACIAS DE CARNEIRO E CAVALO

21
Q

IgM PELO TESTE DE PAUL-BUNNEL

A

AGLUTINACAO DAS HM DE CARNEIRO

22
Q

AGLUTINACAO MAIS SENSIVEL

A

HM DE CAVALO

23
Q

IGM ANTI-VCA

A

TRANSITORIA (4 SEMANAS APOS INFECCAO PRIMARIA) - METODO MAIS ESPECIFICO PARA DDX DE INFECCAO AGUDA

24
Q

IGG ANTI-VCA E ANTI EBNA NEGATIVOS SUGEREM

A

INFECCAO RECENTE

25
Q

COMPLICACAO MAIS TEMIDA

A

RUPTURA ESPLENICA

26
Q

SINDROME REFERIDA

A

ALICE NO PAIS DAS MARAVILHAS

27
Q

COMPLICACOES

A

MIOCARDITE, PNEUMONIA, PANCREATITE, PAROTIDITE, ORQUITE

28
Q

TRATAMENTO

A

NAO HA TRATAMENTO ESPECIFICO
ACICLOVIR NAO REDUZ GRAVIDADE -> NAO E RECOMENDADO
CORTICOTERAPIA CONTROVERSA