Molecules Of Functional Significance : Lipids Flashcards
1.) Lipids are defined as ____ ?
A heterogenous group of naturally occurring compounds which are relatively insoluble in water but freely solvable in nonpolar organic substances.
OR
Long chain hydrocarbon groups that may contain oxygen, phosphorous, nitrogen and sulfur
2) List three functions of lipids.
Triglycerides are a major storage form of energy.
Form important constituents of the cell membrane.
Used for the synthesis of cholesterol.
Maintains membrane structure and integrity.
Aids in blood coagulation.
3.) Which of the the following describes the functions of lipids?
A) aids in blood peptization.
B) forms important constituents of the mitochondria.
C) major storage form of energy.
D) maintains exoskeleton structure and integrity.
C) Major storage form of energy.
4.) Fats and waxes belong to which class of lipids?
A) simple lipids
B) compound lipids
C) derived lipids
D) complex lipids
A) Simple lipids.
5.) Which of the following accurately depict a triglycerol?
A) α1 CH2-OH | β CH-OH + 3 Fatty Acids | α2 CH2-OH
B) α1 CH2-O-CO-R1 | β CH-O-CO-R2 | α2 CH2-O-CO-R3
C) CH2OH | R”OOCH | CH2OH
B) α1 CH2-O-CO-R1 | β CH-O-CO-R2 | α2 CH2-O-CO-R3
6.) Which of the following is false?
A) The R groups indicate the fatty acids.
B) Each R group must be a different fatty acid type.
C) R2 is an unsaturated fatty acid.
B) Each R group must be a different fatty acid type is false because R groups 1 and 3 can either be the same or different fatty groups while R2 is typically an unsaturated fatty acid.
7.) Compound lipids are____?
Esthers of fatty acids with one of the various alcohols and in addition it contains other non lipid components.
8.) _____ contains alcohol, fatty acids, phosphoric acid and choline
A) Cephalines
B) Lecithin
C) Phosphatidyl ethanolamine
D) Phosphatidyl inositol.
B) Lecithin / Phosphatidyl choline
- ) Lecithin is present in which of the following?
i) cardiac tissue, skin, spinal fluid.
ii) bones, liver tissue, bone marrow.
iii) brain, nervous tissue, sperm.
A) i and iii only. B) i and ii only. C) i , ii, and iii. D) iii only. E) ii and iii only
D) lecithin is present in the brain, nervous tissue, sperm and egg yolk
10.) Dipalmitayl lecithin is a lung surfactant which ______.
Lowers surface tension and prevents the collapse of lung alveoli.
11.) What produces respiratory distress syndrome/ hyaline membrane disease in premature infants?
An absence of dipalmitoyl lecithin
12.) Cephalins contain_____ and are present in_____.
A basic phospholipid with ethanolamine as the nitrogenous base
The brain, erythrocytes and many other tissues.
13.) Sphingomyelin is present in?
The brain, lungs and nerves
14.) What is the Niemann-Pick disease?
A deficiency of sphingomyelinase in the liver, lymph nodes, bone marrow and central nervous system.
15.) What is Gaucher’s disease?
An increased level of cerebrosides in tissues like the spleen, liver, lymph nodes and bone.
16.) What disease is characterized by elevated ganglioside levels?
Tay-Sachs disease
17.) Where are Very Low Density Lipoprotiens synthesized?
VLDL are synthesized in the liver and transport endogenous triglycerides from the liver to the extrahepatic tissues.
18.) What are the most abundant phospholipids of the cell membrane?
Lecithins
19.) A glycerol molecule which has one molecule of fatty acid is known as?
Monocylglycerol
20.) Cephalins play a role in which of the following?
A) Apoptosis
B) Diffusion
C) Active Transport
A) Apoptosis i.e. cell death
21.) Phosphatidyl inositol play an important role in?
A) Cell signaling and membrane trafficking for the cell membrane.
B) Translation and Transcription
C) Allowing materials in and out of the cell
A) Cell signaling and membrane trafficking for the cell membrane.
22.) Why are saturated and trans-fat dangerous?
A) They can raise cholesterol level leading to increased risk of heart disease.
B) They can raise blood pressure leading to increased risk of heart disease.
They can raise cholesterol level leading to increased risk of heart disease.
23.) Omega 3 & 6 benefits are:
A) Decreases risk of Alzheimer’s, help maintain a good mood.
B) Influences better mental health and help maintain a well balanced diet.
A) Decreases risk of Alzheimer’s, help maintain a good mood.
24.) Which of the following is an important constituent of plasma membranes?
A) Steroids
B) Fatty Acids
C) Cholesterol
B) Fatty Acids